PLX-4720(5毫克)產(chǎn)品是PLX-4720 is a potent, ATP-competitive B-raf inhibitor (IC?? =160 nM). PLX-4720 preferentially inhibits the active B-Raf(V600E) kinase compared with a broad spectrum of other kinases, and potent cytotoxic effects are also exclusive to cells bearing the V600E allele.?