APG7/ATG7抗體-APG7/ATG7 Antibody代理/參數(shù)/廠家-二抗-艾美捷科技有限公司

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背景資料: Autophagy，the process of bulk degradation of cellular proteins throμgh an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) throμgh phosphorylation of autophagy protein APG1. Another member of the autophagy family of proteins is APG7 which was identified in yeast as a ubiquitin-E1-like enzyme; this function is conserved in the mammalian homolog (4). In mammalian cells，APG7 is essential for autophagy conjμgation systems，autophagosome formation，starvation-induced bulk degradation of proteins and organelles. It has been sμggested that caspase-8 may alter APG7 levels and thus the APG7 program of autophagic cell death.

保存建議: 艾美捷提供的APG7/ATG7抗體產(chǎn)品，請(qǐng)將該產(chǎn)品置于-20 °C冷凍保存，建議分裝使用以避免反復(fù)凍融。

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