中文名稱

【PGRN】人源細胞表達的再生大鼠顆粒蛋白前體（50 ug）

英文名字

Human CellExp Progranulin, Rat Recombinant

供應商

Biovision

產(chǎn)品貨號

4735-50

產(chǎn)品報價

￥已停產(chǎn)

產(chǎn)品說明書

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購買方式

銀行轉賬、電匯、支票、現(xiàn)金，在線支付寶及網(wǎng)銀支付，或直接與我們電話聯(lián)系400-6800-868.

產(chǎn)品新聞

背景資料

Progranulin (PGRN), also called proepithelin and PC cell-derived growth factor, is a single precursor protein of granulins which are a family of secreted, glycosylated peptides. It is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of fronto-temporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. Progranulin is a biomarker for FTLD, other types of Alzheimer‘s Disease (AD) and potentially for MCI (Mild Cognitive Impairment). Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis. Rat Recombinant Progranulin fused to FLAG at C-terminus produced in HEK is a single, glycosylated, polypeptide chain purified by standard chromatographic techniques, containing 602 amino acids and having a molecular mass of ~65.0 kDa.

序列

人源細胞表達的重組大鼠顆粒蛋白前體蛋白產(chǎn)品，又稱Proepithelin; PEPI; PC Cell-derived Growth Factor.其對應NCBI基因號為10116，對應Accession號為P23785.

來源宿主

提供的【PGRN】人源細胞表達的重組大鼠顆粒蛋白前體產(chǎn)品的來源為人胚胎腎HEK293細胞重組表達重組表達.

溶解建議

人源細胞表達的重組大鼠顆粒蛋白前體產(chǎn)品請按照說明書建議進行溶解操作：Reconstitute in dH2O before use.

保存建議

在您收到艾美捷發(fā)出的【PGRN】人源細胞表達的重組大鼠顆粒蛋白前體產(chǎn)品后，建議將其置于-20°C保存.

其他

BioVision的公司總部在美麗的舊金山灣地區(qū)，它是全球生命科學公司的Leader，BioVision在開發(fā)和研究細胞凋亡檢測分析、代謝檢測方面具有卓越的影響力.包括檢測各種檢測分析試劑盒、相關特色抗體、重組蛋白及細胞因子和酶等多種產(chǎn)品，以及其他創(chuàng)新的研究工具.其產(chǎn)品覆蓋細胞凋亡研究、能量代謝、細胞/組織蛋白提取、氧化應激與損傷、代謝與肥胖癥、細胞增殖與毒性、信號轉導、干細胞研究等領域.作為多家知名品牌的中國總代理以及中國區(qū)域代理，艾美捷與BioVision一起為研究者們提供優(yōu)質(zhì)、新的細胞生物學研究工具而不斷擴大產(chǎn)品及服務質(zhì)量.

注意

該頁面的中文產(chǎn)品信息的翻譯，僅供參考。準確的產(chǎn)品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。

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