ATG16抗體（中間區(qū)域）-ATG16 Antibody （Center）（Autophagy protein 16， Autophagy related protein 16， ATG16L， APG16）代理/參數(shù)/廠家-二抗-艾美捷科技有限公司

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英文名字: ATG16 Antibody （Center）（Autophagy protein 16， Autophagy related protein 16， ATG16L， APG16）

購(gòu)買(mǎi)方式: 銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金，在線支付寶及網(wǎng)銀支付，或直接與我們電話聯(lián)系400-6800-868.

背景資料: Autophagy，the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR （Target of rapamycin） through phosphorylation of autophagy protein APG1. ATG16，another member of the autophagy protein family，forms a complex with the ATG5-ATG12 conjugate. This multimeric protein has been shown to be essential for autophagosome formation in both yeast and mammals and targets the ATG5-ATG12 complex to the autophagic isolation membrane during the formation of the autophagosome. Because mammalian ATG16 has seven WD-repeats in its C-terminal domain，it has been suggested that these may form a platform for further protein-protein interactions. Multiple isoforms of ATG16 are known to exist.

應(yīng)用類型: Western Blot: 0.25 – 0.5 ug/ml， Immunocytochemistry: 2 ug/ml， ELISA. However， the optimal conditions should be determined individually.

免疫原: ATG16 antibody was raised against a 18 amino acid peptide from near the center of human ATG16.

反應(yīng)性: 經(jīng)檢測(cè)驗(yàn)證，可與人、小鼠、大鼠種屬來(lái)源的ATG16抗體（中間區(qū)域）蛋白發(fā)生免疫反應(yīng).

保存建議: 提供的ATG16抗體（中間區(qū)域）產(chǎn)品為無(wú)色溶液形式，含有100 ug抗體.該產(chǎn)品濃度為1 mg/ml，溶解于包含有0.02 % 疊氮化鈉的PBS緩沖液中.請(qǐng)?jiān)谑盏皆揂TG16抗體（中間區(qū)域）產(chǎn)品后，將其置于-20 °C冷凍保存，建議分裝使用以避免反復(fù)凍融.

其他: BioVision的公司總部在美麗的舊金山灣地區(qū)，它是全球生命科學(xué)公司的Leader，BioVision在開(kāi)發(fā)和研究細(xì)胞凋亡檢測(cè)分析、代謝檢測(cè)方面具有卓越的影響力.包括檢測(cè)各種檢測(cè)分析試劑盒、相關(guān)特色抗體、重組蛋白及細(xì)胞因子和酶等多種產(chǎn)品，以及其他創(chuàng)新的研究工具.其產(chǎn)品覆蓋細(xì)胞凋亡研究、能量代謝、細(xì)胞/組織蛋白提取、氧化應(yīng)激與損傷、代謝與肥胖癥、細(xì)胞增殖與毒性、信號(hào)轉(zhuǎn)導(dǎo)、干細(xì)胞研究等領(lǐng)域.作為多家知名品牌的中國(guó)總代理以及中國(guó)區(qū)域代理，艾美捷與BioVision一起為研究者們提供優(yōu)質(zhì)、新的細(xì)胞生物學(xué)研究工具而不斷擴(kuò)大產(chǎn)品及服務(wù)質(zhì)量.