LSD1（aa 800-850）抗體-LSD1 （aa 800-850） Antibody （Lysine-specific histone demethylase 1A （BRAF35-HDAC complex protein BHC110）（Flavin-containing amine oxidase domain-containing protein 2））代理/參數(shù)/廠家-二抗-艾美捷科技有限公司

PRODUCT CENTER

二抗

產品中心

當前位置：首頁 > 產品中心 > 免疫學產品 > 二抗

英文名字: LSD1 （aa 800-850） Antibody （Lysine-specific histone demethylase 1A （BRAF35-HDAC complex protein BHC110）（Flavin-containing amine oxidase domain-containing protein 2））

背景資料: LSD1 the first known lysine-specific histone demethylase， is an 866 amino acid nuclear protein belonging to flavin monoamine oxidase family. It contains a SWIRM domain， a FAD-binding motif and an amine oxidase domain. This protein is ubiquitously expressed and is a component of several histone deacetylase complexes. LSD1 acts as a component of the CoREST and other transcriptional co-repressor complexes and also plays an important role in silencing neuronal-specific genes in non-neuronal cells. It is also known to demethylate Lys4 of histone H3， a specific tag for epigenetic transcriptional activation. Reports suggest that that LSD1 plays an important role in stimulating androgen-receptor-dependent transcription converting oxygen to hydrogen peroxide （might use alternative electron acceptors）. Along with nuclear FHL2， LSD1 serves as a novel biomarker predictive for prostate cancer.

應用類型: Western blot: 1-3 ug/ml， IHC （paraffin embedded sections）: 10 ug/ml. However， the optimal conditions should be determined individually.

保存建議: 提供的LSD1 （aa 800-850）抗體產品為無色溶液形式，含有50 ug抗體.該產品濃度為與批次相關，溶解于包含有0.2% gelatin和0.05%疊氮化鈉的PBS緩沖液中..請在收到該LSD1 （aa 800-850）抗體產品后，將其置于-20 °C冷凍保存，建議分裝使用以避免反復凍融.

其他: BioVision的公司總部在美麗的舊金山灣地區(qū)，它是全球生命科學公司的領導者.BioVision在開發(fā)和研究細胞凋亡檢測分析、代謝檢測方面具有卓越的影響力.包括檢測各種檢測分析試劑盒、相關特色抗體、重組蛋白及細胞因子和酶等多種產品，以及其他創(chuàng)新的研究工具.其產品覆蓋細胞凋亡研究、能量代謝、細胞/組織蛋白提取、氧化應激與損傷、代謝與肥胖癥、細胞增殖與毒性、信號轉導、干細胞研究等領域.作為多家知名品牌的中國總代理以及中國區(qū)域代理，艾美捷與BioVision一起為研究者們提供最好、最新的細胞生物學研究工具而不斷擴大產品及服務質量.