This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3,-7,-9 and 10 to give rise to active enzymes mediating apoptosis.
應(yīng)用類型
Western blot
免疫原
顆粒酶B抗體Granzyme B Antibody該產(chǎn)品的免疫原查閱產(chǎn)品說(shuō)明書(shū)。