ANGPTL1抗體（N末端）-ANGPTL1 Antibody （NT）（ANGPTL1； ANG3； ANGPT3； ARP1； Angiopoietin-related protein 1； Angiopoietin-3； Angiopoietin-like protein 1）代理/參數(shù)/廠家-二抗-艾美捷科技有限公司

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英文名字: ANGPTL1 Antibody （NT）（ANGPTL1； ANG3； ANGPT3； ARP1； Angiopoietin-related protein 1； Angiopoietin-3； Angiopoietin-like protein 1）

背景資料: Angptl1 （angiopoietin-like 1），also known as angioarrestin，ARP1，ANGPT3 or previously known as angiopoietin 3 （ANG3），is a member of the angiopoietin-like family. It is highly expressed in adult tissues，particularly adrenal gland，thyroid，placenta and small intestine. Angptl1 exists as a disulfide-linked dimer and shares 45.1% identity with Ang-1 and 59% identity with Angptl2. Angptl1 consists of an N-terminus with a coiled-coil domain，potential glycosylation sites and a C-terminus with a fibrinogen-like domain. It is a secreted protein but does not function as a growth factor in endothelial cells. Angptl1 plays a distinct role in the regulation of angiogenesis； inhibiting proliferation，migration，tube formation and endothelial cell adhesion. To exert this inhibitory activity，Angptl1 is speculated to interact with a receptor on endothelial cells. In a wide variety of tumor tissues，Angptl1 expression is down-regulated suggesting that a major function of this protein involves its antiangiogenic properties.

免疫原: This ANGPTL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-44 amino acids from the N-terminal region of human ANGPTL1.

保存建議: 提供的ANGPTL1抗體（N末端）產(chǎn)品為無色溶液形式，含有100 ul抗體.該產(chǎn)品濃度為與批次相關，溶解于包含有0.09% （W/V）疊氮化鈉的PBS緩沖液中.請在收到該ANGPTL1抗體（N末端）產(chǎn)品后，將其置于-20 °C冷凍保存，建議分裝使用以避免反復凍融.

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