CD11c FITC重組抗體（克隆號(hào)3.9）-CD11c FITC Monoclonal Antibody (Clone 3.9)代理/參數(shù)/廠家-二抗-艾美捷科技有限公司

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中文名稱: CD11c FITC重組抗體（克隆號(hào)3.9）

英文名字: CD11c FITC Monoclonal Antibody (Clone 3.9)

供應(yīng)商: Biovision

產(chǎn)品貨號(hào): 6956-100

產(chǎn)品報(bào)價(jià): ￥已停產(chǎn)

產(chǎn)品說(shuō)明書(shū): 點(diǎn)擊查看

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背景資料: CD3 (T3)，a complex T cell marker，is known to associate noncovalently with the a/b or g/z heterodimer of the T cell antigen receptor (TCR) to form the most complex transmembrane (TM) receptor structures. CD3 is specially engaged in antigen recognition and is known to play an important role in mediating signals that are critical for T cell development in the thymus，proliferation，and induction of T cell-mediated immune responses against infectious agents and also in the differentiation of T cells into effector and memory populations. CD3 usually expresses in the cytoplasm of prothymocytes，and on the surface of about 95% of thymocytes，but cytoplasmic CD3 is lost as the cells differentiate into medullary thymocytes. Apart from its role as an important marker in the classification of malignant lymphomas and lymphoid leukemia，CD3 can also be useful for the identification of T cells in celiac disease，lymphocytic colitis and colorectal carcinomas associated with loss of a mismatch repair protein. CD3 indirectly plays an important role in immunomodulation whereas the anti-CD3 antibody may be used in in vitro Treg assays to generate effector T cells. The CD3 complex contains γ，δ，and ε chains，and it is part of the TCR complex，expressed by all mature T lymphocytes and by the thymocyte lineage. The OKT3 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. CD3 enhances the antigen recognition by signal transduction. The OKT3 antibody is an immunosuppressive，which has proven to be an effective therapeutic agent in liver，heart，and renal allograft rejection.

應(yīng)用類型: Flow cytometry

免疫原: Human CD11c

來(lái)源宿主: 小鼠

反應(yīng)性: 經(jīng)檢測(cè)驗(yàn)證，可與人種屬來(lái)源的CD11c蛋白發(fā)生免疫反應(yīng).

保存建議: 提供的CD11c FITC單克隆抗體 (克隆號(hào)3.9)產(chǎn)品為無(wú)色液體.建議使用冰袋運(yùn)輸，收到產(chǎn)品后，請(qǐng)4°C儲(chǔ)存.該產(chǎn)品有效期為12個(gè)月.

其他: BioVision的公司總部在美麗的舊金山灣地區(qū)，它是全球生命科學(xué)公司的Leader，BioVision在開(kāi)發(fā)和研究細(xì)胞凋亡檢測(cè)分析、代謝檢測(cè)方面具有卓越的影響力.包括檢測(cè)各種檢測(cè)分析試劑盒、相關(guān)特色抗體、重組蛋白及細(xì)胞因子和酶等多種產(chǎn)品，以及其他創(chuàng)新的研究工具.其產(chǎn)品覆蓋細(xì)胞凋亡研究、能量代謝、細(xì)胞/組織蛋白提取、氧化應(yīng)激與損傷、代謝與肥胖癥、細(xì)胞增殖與毒性、信號(hào)轉(zhuǎn)導(dǎo)、干細(xì)胞研究等領(lǐng)域.作為多家知名品牌的中國(guó)總代理以及中國(guó)區(qū)域代理，艾美捷與BioVision一起為研究者們提供優(yōu)質(zhì)、新的細(xì)胞生物學(xué)研究工具而不斷擴(kuò)大產(chǎn)品及服務(wù)質(zhì)量.