Nimesulide is a selective inhibitor of COX-2. The IC50 values are 70 and 1.27 uM for human recombinant COX-1 and -2 (at 20 uM arachidonic acid), respectively, and 22 and 0.03 uM for ovine COX-1 and -2 (at 100 uM arachidonic acid), respectively.
產(chǎn)品描述
Nimesulide is a selective inhibitor of COX-2. The IC50 values are 70 and 1.27 uM for human recombinant COX-1 and -2 (at 20 uM arachidonic acid), respectively, and 22 and 0.03 uM for ovine COX-1 and -2 (at 100 uM arachidonic acid), respectively.{1364,1286}