Retinol binding protein 4 (RBP4; RBP) is a 21 kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity, and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function.
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人源細胞表達的重組大鼠視黃醇結合蛋白4蛋白產品,又稱Retinol Binding Protein 4, Plasma retinol-binding protein, PRBP, RBP.其對應NCBI基因號為25703,對應Accession號為P04916.