中文名稱

【LCN 2】人源細(xì)胞表達(dá)的重組大鼠重組移植蛋白-2 / LCN2（10 ug）

英文名字

Human CellExp Lipocalin-2 / LCN2, rat recombinant

供應(yīng)商

Biovision

產(chǎn)品貨號

7569-10

產(chǎn)品報(bào)價(jià)

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產(chǎn)品新聞

背景資料

Lipocalin-2 (LCN2), also known as oncogene 24p3 or neutrophil gelatinase-associated lipocalin (NGAL), MSFI, The binding of lipocalin-2 to bacterial siderophores is important in the innate immune response to bacterial infection. Upon encountering invading bacteria the toll-like receptors on immune cells stimulate the synthesis and secretion of lipocalin-2. Secreted lipocalin-2 then limits bacterial growth by sequestering iron-containing siderophores. Lipocalin-2 also functions as a growth factor. LCN2 is strongly upregulated during inflammation and is upregulated by interleukin 1 (but not TNF alpha) in humans. There are indications that some forms of acne could be caused due to the gene not being transcribed, and that Isotretinoin corrects this. NFAT3 (NFATc4) NFAT by blocking the expression of LCN2 inhibits breast carcinoma cell motility. Recent studies have revealed that NGAL plays an important role in the physiopathology of chronic myeloid leukaemia (CML) mediated by BCR-ABL.

序列

人源細(xì)胞表達(dá)的重組大鼠脂質(zhì)運(yùn)載蛋白-2/LCN2蛋白產(chǎn)品，又稱NGAL, LCN2, Lipocalin-2, 24p3, MSFI, Siderocalin; Oncogene 24p3; Neutrophil Gelatinase-associated Lipocalin; NGAL.其對應(yīng)NCBI基因號為170496，對應(yīng)Accession號為P30152.

來源宿主

提供的【LCN 2】人源細(xì)胞表達(dá)的重組大鼠脂質(zhì)運(yùn)載蛋白-2/LCN2產(chǎn)品的來源為人胚腎HEK293細(xì)胞重組表達(dá)重組表達(dá).

溶解建議

人源細(xì)胞表達(dá)的重組大鼠脂質(zhì)運(yùn)載蛋白-2/LCN2產(chǎn)品為液體即用型，其溶液組成為：0.2 um-filtered solution in PBS

保存建議

在您收到艾美捷發(fā)出的【LCN 2】人源細(xì)胞表達(dá)的重組大鼠脂質(zhì)運(yùn)載蛋白-2/LCN2產(chǎn)品后，建議將其置于-20°C保存.

其他

BioVision的公司總部在美麗的舊金山灣地區(qū)，它是全球生命科學(xué)公司的Leader，BioVision在開發(fā)和研究細(xì)胞凋亡檢測分析、代謝檢測方面具有卓越的影響力.包括檢測各種檢測分析試劑盒、相關(guān)特色抗體、重組蛋白及細(xì)胞因子和酶等多種產(chǎn)品，以及其他創(chuàng)新的研究工具.其產(chǎn)品覆蓋細(xì)胞凋亡研究、能量代謝、細(xì)胞/組織蛋白提取、氧化應(yīng)激與損傷、代謝與肥胖癥、細(xì)胞增殖與毒性、信號轉(zhuǎn)導(dǎo)、干細(xì)胞研究等領(lǐng)域.作為多家知名品牌的中國總代理以及中國區(qū)域代理，艾美捷與BioVision一起為研究者們提供優(yōu)質(zhì)、新的細(xì)胞生物學(xué)研究工具而不斷擴(kuò)大產(chǎn)品及服務(wù)質(zhì)量.

注意

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