【PPARG】重組人過氧化物酶增殖物激活受體γ（LBD）（His-tagged）-PPARγ (LBD) Human Recombinant (His-tagged)代理/參數(shù)/廠家-重組蛋白-艾美捷科技有限公司

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背景資料: The peroxisome proliferator activated receptor (PPAR) family of ligand-activated transcription factors consists of three subtypes encoded by separate genes: PPARα, PPARδ and PPARγ. Of these, PPARγ plays an important role in the regulation of fatty acid storage and glucose metabolism. The genes activated by PPARγ stimulate lipid uptake and adipogenesis by fat cells. Many naturally occurring molecules such as, polyunsaturated fatty acids like arachidonic acid and arachidonic acid metabolites, are known to bind and activate PPARγ. The binding of activating ligands to the ligand binding domain (LBD) of PPARγ promotes its heterodimerization with retinoic acid-like receptor (RXR), which results in the regulated expression of target genes involved in lipid metabolism. BioVision’s His-PPARγ (LBD) is a non-glycosylated protein expressed and purified from E. coli. It has been tested for functionality by its binding and subsequent displacement of 1,8-ANS assay.

序列: 重組人過氧化物酶增殖物激活受體γ (LBD) (His-tagged)又稱PPAR-gamma, Peroxisome Proliferator-activated Receptor γ Ligand Binding Domain, PPAR-gamma (LBD), NR1C3, PPARG (LBD).其對應NCBI基因號為5468.

溶解建議: 提供的重組人過氧化物酶增殖物激活受體γ (LBD) (His-tagged)產(chǎn)品為溶液形式..溶液為：50 mM Tris, 100 mM NaCl, 1 mM TCEP, pH 8.0 containing 20% glycerol推薦使用如下緩沖液：50 mM Tris, 100 mM NaCl, 1 mM TCEP, pH 8.0 containing 20% glycerol進行進一步的稀釋，濃度為0.5mg/ml.推薦分裝保存于-80℃. 請避免反復凍融！.

保存建議: 艾美捷推薦干冰運輸【PPARG】重組人過氧化物酶增殖物激活受體γ (LBD) (His-tagged)產(chǎn)品.我們建議您收到該產(chǎn)品后將其置于-80°C保存.產(chǎn)品有效期為收到產(chǎn)品后6個月.

其他: BioVision的公司總部在美麗的舊金山灣地區(qū)，它是全球生命科學公司的Leader，BioVision在開發(fā)和研究細胞凋亡檢測分析、代謝檢測方面具有卓越的影響力.包括檢測各種檢測分析試劑盒、相關特色抗體、重組蛋白及細胞因子和酶等多種產(chǎn)品，以及其他創(chuàng)新的研究工具.其產(chǎn)品覆蓋細胞凋亡研究、能量代謝、細胞/組織蛋白提取、氧化應激與損傷、代謝與肥胖癥、細胞增殖與毒性、信號轉導、干細胞研究等領域.作為多家知名品牌的中國總代理以及中國區(qū)域代理，艾美捷與BioVision一起為研究者們提供優(yōu)質(zhì)、新的細胞生物學研究工具而不斷擴大產(chǎn)品及服務質(zhì)量.