中文名稱

5(S),14(R)-Lipoxin B4 (500 ug)

英文名字

5(S),14(R)-LXB4, 5(S),14(R)-Lipoxin B4, 5S,14R,15S-trihydroxy-6E,8Z,1E,12E-eicosatetraenoic acid

供應(yīng)商

Cayman

產(chǎn)品貨號(hào)

90420-500

產(chǎn)品報(bào)價(jià)

￥47712/500 ug

產(chǎn)品說明書

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背景資料

Lipoxins are a series of anti-inflammatory lipid mediators whose brief appearance generally signals the resolution of inflammation. Lipoxin A4 (LXA4) is a potent inhibitor of leukotriene (LT)-triggered polymorphonuclear neutrophil (PMN)-endothelial cell interaction and also blocks PMN migration stimulated by LTB4. LXB4 is a positional isomer of LXA4 produced by the metabolism of 15-HETE or 15-HpETE by human leukocytes. At a concentration of 10-7 M, LXB4 inhibits PMN migration stimulated by LTB4 and inhibits LTB4-induced adhesion of PMNs with an IC50 value of ~3 X 10-10 M.

產(chǎn)品描述

A positional isomer of LXA4 produced by the metabolism of 15-HETE or 15-HpETE by human leukocytes; inhibits PMV migration stimulated by LTB4 at a concentration of 10-7 M and inhibits LTB4-induced adhesion of PMNs with an IC50 value of ~3 x 10-10 M

產(chǎn)品形式

保存建議

-80

其他

Cayman Chemical

注意

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