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中文名稱

大鼠TRPV1 (胞外)抗體

英文名字
rat TRPV1 (extracellular) Antibody
供應(yīng)商
Abgent
產(chǎn)品貨號
A-AG1453
產(chǎn)品報價
¥3025/25 ul
產(chǎn)品說明書
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背景資料
TRP channels are a large family (about 28 genes) of plasma membrane, non-selective cationic channels that are either specifically or ubiquitously expressed in excitable and non-excitable cells.1
 
According to IUPHAR the TRP family comprises of three main subfamilies on the basis of sequence homology; TRPC, TRPM and TRPV (to date, three extra subfamilies are considered to belong to the TRP family; the TRPA, TRPML, and TRPP).1-4 The TRPV subfamily consists of six members, TRPV1-6.5
 
TRPV1 channel has many activators among them heat, protons, vanilloids like capsaicin, reiniferatoxin (RTX), and lipids. This channel is associated with tissue injury and inflammation.6,7
 
TRPV1 is expressed predominantly in nociceptors and in sensory neurons.
  
Recent studies demonstrated involvement of TRPV1 in apoptosis where inhibition of the receptor prevented apoptosis.8,9
 
Alomone Labs is pleased to offer a highly specific antibody directed against an extracellular  epitope of the rat TRPV1 channel. Anti-Rat TRPV1 (extracellular) antibody (#AG1453) can be used for western blot and immunohistochemistry applications. It has been designed to recognize only rat TRPV1 samples.
應(yīng)用類型
WB
免疫原
O35433
來源宿主
反應(yīng)性
保存建議
其他
ABGENT
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