OX40 is also known as CD134 is a member of the tumor necrosis factor receptor superfamily (TNFR). OX40 plays an important role in CD4+ and CD8+T-cells and B-cells response. Binding of OX40 to its ligand,OX40L provides co-stimulatory signal to effector T-cells without CD28 activation.
應(yīng)用類型
抗OX40L(Oxelumab),人類IgG1抗體Anti-OX40L (Oxelumab), Human IgG1 Antibody該產(chǎn)品的應(yīng)用類型查閱產(chǎn)品說明書。
免疫原
Oxelumab binds to human OX40L, the ligand of OX40, stimulatory receptor that is expressed on activated T cells, natural killer (NK) cells and natural killer T (NKT) cells.