Integrin alpha-L/beta-2 is a receptor for ICAM1,ICAM2,ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction,cytotoxic T-cell mediated killing,and antibody dependent killing by granulocytes and monocytes.
應(yīng)用類型
抗CD11a(依法珠單抗),人類IgG1抗體Anti-CD11a (Efalizumab), Human IgG1 Antibody該產(chǎn)品的應(yīng)用類型查閱產(chǎn)品說明書。
免疫原
Efalizumab binds to CD11a, a subunit of leukocyte function antigen-1 (LFA-1), which is expressed on all leukocytes.