Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit
應(yīng)用類(lèi)型
WB, IF/IC
免疫原
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ASF1A