抗ACTH抗體（r57）-Anti-ACTH Antibody (r57)代理/參數(shù)/廠家-二抗-艾美捷科技有限公司

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背景資料: ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This mAb is specific to CLIP (aa 25-39 of ACTH); does not react with Synacthen (aa1-24 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive，tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP，ACTH，alpha-MSH (Melanocyte Stimulating Hormone)，beta-MSH，gamma-MSH，CLIP (corticotropin-like intermediary peptide)，Lipotropin-beta，Lipotropin-gamma，beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells，B-cells，and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.

來(lái)源宿主: 提供的抗ACTH抗體（r57）Anti-ACTH Antibody (r57)產(chǎn)品，該來(lái)源宿主查看產(chǎn)品說(shuō)明書。

保存建議: 艾美捷提供的抗ACTH抗體（r57）產(chǎn)品，請(qǐng)將該產(chǎn)品置于-20oC冷凍保存，建議分裝使用以避免反復(fù)凍融。

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