Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development,synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1,alpha-9/beta-1,alpha-V/beta-3 and alpha-V/beta-6. In tumors,stimulates angiogenesis by elongation,migration and sprouting of endothelial cells.
應用類型
WB, ELISA
免疫原
A synthesized peptide derived from human TNC
來源宿主
提供的抗Tenascin C抗體Anti-Tenascin C Antibody產品,該來源宿主查看產品說明書。