抗DDIT3抗體-Anti-DDIT3 Antibody代理/參數(shù)/廠家-二抗-艾美捷科技有限公司

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背景資料: Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer-binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family，impairs their association with C/EBP binding sites in the promoter regions，and inhibits the expression of C/EBP regulated genes. ositively regulates the transcription of TRIB3，IL6，IL8，IL23，TNFRSF10B/DR5，PPP1R15A/GADD34，BBC3/PUMA，BCL2L11/BIM and ERO1L. Negatively regulates; expression of BCL2 and MYOD1，ATF4-dependent transcriptional activation of asparagine synthetase (ASNS)，CEBPA-dependent transcriptional activation of hepcidin (HAMP) and CEBPB-mediated expression of peroxisome proliferator-activated receptor gamma (PPARG).

免疫原: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human DDIT3

來(lái)源宿主: 提供的抗DDIT3抗體Anti-DDIT3 Antibody產(chǎn)品，該來(lái)源宿主查看產(chǎn)品說(shuō)明書。

保存建議: 艾美捷提供的抗DDIT3抗體產(chǎn)品，請(qǐng)將該產(chǎn)品置于-20oC冷凍保存，建議分裝使用以避免反復(fù)凍融。

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