Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5.蛋白別名為:AGBL4; CCP6; Cytosolic carboxypeptidase 6; ATP/GTP-binding protein-like 4;基因ID為:84871;蛋白質(zhì)ID:Q5VU57
應(yīng)用類型
WB,ELISA補充:最優(yōu)的抗體稀釋比例需要基于客戶實驗進(jìn)行優(yōu)化.建議的起始稀釋比例如下: WB: 1:500-1:2000, ELISA: 1:20000. Not yet tested in other applications.
免疫原
合成多肽:the C-terminal region of human AGBL4. at AA rangle: 400-480