T-complex protein 1 subunit zeta encoded by CCT6A is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, several pseudogenes of this gene have been located. 蛋白別名為:CCT6A; CCT6; CCTZ; T-complex protein 1 subunit zeta; TCP-1-zeta; Acute morphine dependence-related protein 2; CCT-zeta-1; HTR3; Tcp20;基因ID為:908;蛋白質(zhì)ID:P40227
應(yīng)用類型
WB,IHC-p,ELISA補充:最優(yōu)的抗體稀釋比例需要基于客戶實驗進行優(yōu)化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human TCP-1 ζ. at AA rangle: 140-220