TFIIH p44 多克隆抗體-TFIIH p44 Polyclonal Antibody代理/參數(shù)/廠家-一抗-艾美捷科技有限公司

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背景資料: GTF2H2 is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. GTF2H2 is within the telomeric copy of the duplication. Deletion of this gene sometimes accompanies deletion of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients but it is unclear if deletion of this gene contributes to the SMA phenotype. This gene encodes the 44 kDa subunit of RNA polymerase II transcription initiation factor IIH which is involved in basal transcription and nucleotide excision repair. Transcript variants for this gene have been described, but their full length nature has not been determined. A second copy of this gene within the centromeric copy of the duplication has been described in the literature. It is reported to be different by either two or four base pairs; however, no sequence data is currently available for the centromeric copy of the gene.
蛋白別名為：GTF2H2; BTF2P44; General transcription factor IIH subunit 2; Basic transcription factor 2 44 kDa subunit; BTF2 p44; General transcription factor IIH polypeptide 2; TFIIH basal transcription factor complex p44 subunit;基因ID為：2966；蛋白質(zhì)ID:Q13888

應(yīng)用類型: WB，IHC-p，IF，ELISA
補(bǔ)充：最優(yōu)的抗體稀釋比例需要基于客戶實(shí)驗(yàn)進(jìn)行優(yōu)化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, IF: 1:200-1:1000, ELISA: 1:40000. Not yet tested in other applications.

保存建議: 廠家推薦藍(lán)冰運(yùn)輸.在發(fā)貨后能在-20℃保存1年.為最大限度的避免損失，請(qǐng)?jiān)诖蜷_管蓋之前融化抗體并離心.我們建議使用前分裝以避免反復(fù)凍融.
本產(chǎn)品為液體形式,溶解于PBS緩沖液中，含50%甘油，0.5%BSA和0.02%NaN3.

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