CDK11A(cyclin dependent kinase 11A) encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, CDK11A shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by CDK11A can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants.蛋白別名為:CDK11A; CDC2L2; CDC2L3; PITSLREB; Cyclin-dependent kinase 11A; Cell division cycle 2-like protein kinase 2; Cell division protein kinase 11A; Galactosyltransferase-associated protein kinase p58/GTA; PITSLRE serine/threonine-protein kinase C;基因ID為:728642/984;蛋白質(zhì)ID:Q9UQ88/P21127
應(yīng)用類型
WB,ELISA補充:最優(yōu)的抗體稀釋比例需要基于客戶實驗進(jìn)行優(yōu)化.建議的起始稀釋比例如下: WB: 1:500-1:2000, ELISA: 1:10000. Not yet tested in other applications.
免疫原
合成多肽:the Internal region of human Cdk11A/B. at AA rangle: 190-270