卵母細(xì)胞成熟質(zhì)量（OMQ）檢查抑制素 A ELISA-Oocyte Maturation Quality (OMQ) Check Inhibin A ELISA代理/參數(shù)/廠家-ELISA試劑盒-艾美捷科技有限公司

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中文名稱: 卵母細(xì)胞成熟質(zhì)量（OMQ）檢查抑制素 A ELISA

英文名字: Oocyte Maturation Quality (OMQ) Check Inhibin A ELISA

供應(yīng)商: Ansh Labs

產(chǎn)品貨號(hào): AL-1009

產(chǎn)品報(bào)價(jià): ￥詢價(jià)/96wellmicrotiter

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背景資料: Inhibins are heterodimeric protein hormones secreted by granulosa cells of the ovary in the female and Sertoli cells of the testis in the male. They selectively suppress the secretion of pituitary follicle stimulating hormone (FSH) and have local paracrine actions in the gonads. The fully processed form of the inhibin molecule has a molecular weight of approximately 32 kD and consists of the two distinct chains (α and β), linked by disulfide bridges. Higher molecular weight forms, with precursor forms of the α-subunit, also occur in follicular fluid and serum. In addition, free α-subunit forms, unassociated with a β-subunit, and lacking inhibin bioactivity, are also present. Inhibin A consists of an α-subunit and βA-subunit.
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nRecently, Inhibin-A and Inhibin-B are emerging as markers for the assessment of developing follicles during ovarian stimulation.1 and can assist with the follicle dynamics. The number of mature oocytes is a key factor in the IVF success. Gonadotropin dosing during ovarian stimulation cycle is a critical step in maximizing the oocytes yield. The serum estradiol and transvaginal ultrasound measurements are currently used as monitoring tools in stimulated cycle. Serum Estradiol levels are commonly supraphysiological and often variable due to multi-follicular growth of varying size of follicles in IVF cycles. Additionally, Estradiol binds to peripheral SHBG and the competitive nature of the immunoassay makes Estradiol measurement unreliable for checking the oocyte maturation quality. In contrast, serum Inhibin A levels increase only when follicle size are between 12–15 mm. This makes serum Inhibin-A a better marker for studying the Oocyte quality. Along with routine ultrasound measurements, Inhibin A has been studied for optimal timing of trigger medication with a threshold of ≥10 mature oocytes.1 Serum Inhibin-A levels strongly correlate to the number of follicles ≥15mm and mature oocytes. Measurements of Inhibin-A are shown to be useful in studying its role in human reproductive physiology.1
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nReference:
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n1 Barbara Lawrenz, Leyla Depret Bixio, Carol Coughlan, Claus Yding Andersen, Laura Melado, Bhanu Kalra, Gopal Savjani, Human M. Fatemi and Ajay Kumar; Inhibin A- A promising predictive parameter for determination of final oocyte maturation in ovarian stimulation for IVF/ICSI (2020)

產(chǎn)品描述: The Oocyte Maturation Quality (OMQ) Check enzyme linked immunosorbent assay (ELISA) kit provides materials for the quantitative measurement of dimeric Inhibin A in human serum.

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保存建議: Store at 2 to 8°C until expiration date.

其他: Ansh labs是開(kāi)發(fā)和生產(chǎn)免疫檢測(cè)試劑盒和定制生物技術(shù)檢測(cè)產(chǎn)領(lǐng)創(chuàng)者，總部位于美國(guó)休斯敦，公司產(chǎn)品遍及全球80多個(gè)國(guó)家。公司于2011年成立，核心團(tuán)隊(duì)來(lái)自于Diagnostic system laboratory，專注于女性健康和激素檢測(cè)領(lǐng)域近40年，擁有全球領(lǐng)先的核心技術(shù)，以及多年經(jīng)驗(yàn)生物技術(shù)研發(fā)經(jīng)驗(yàn)的科學(xué)家團(tuán)隊(duì)，產(chǎn)品覆蓋生殖健康，高危妊娠，腫瘤，糖尿病等多個(gè)疾病領(lǐng)域，圍繞最新的免疫分析技術(shù)，多種蛋白和單克隆抗體，如AMH，BMP-15, Follistatin, GDF-9, IGF-I, IGF-II, IGFBP-2, IGFBP-3, IGFBP-4, IGFBP-5, Inhibin Alpha, Inhibin ?A, Inhibin ?B, MBP, PAPP-A, PAPP-A2 and Vitamin D.等幾十余種試劑產(chǎn)品，也同時(shí)涵蓋小鼠，大鼠，狗，羊，牛等靈長(zhǎng)類多個(gè)物種的獨(dú)特的物種特異性的試劑。 Ansh labs 坐落于美國(guó)德克薩斯州，是目前世界上唯一能提供TGF-β超家族所有成員的檢測(cè)公司，也是最早專注激素類產(chǎn)品研究和新型免疫檢測(cè)技術(shù)的先驅(qū)者。優(yōu)勢(shì)產(chǎn)品涉及TGF-β super family、AMH/抑制素B(human/animal)、full panel IGFs、以及最完整的胰高血糖素系列。