帕普-A ELISA-PAPP-A ELISA代理/參數(shù)/廠家-ELISA試劑盒-艾美捷科技有限公司

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背景資料: Maternal serum concentrations of pregnancy-associated plasma protein A (PAPP-A, EC 3.4.24.79, papalysin-1) are used to predict occurrence of Down syndrome. During pregnancy, PAPP-A is produced in high concentrations by the trophoblast and released into maternal circulation. In pregnancy, PAPP-A primarily circulates as 500-kDa heterotetrameric 2:2 complex with the proform of eosinophil major basic protein (proMBP), which inhibits the proteolytic activity of PAPP-A. Dimeric PAPP-A is the only active form and proteolyses IGFBP-4 and IGFBP-5. Significant amounts of active PAPP-A is reported at gestational ages between seven and thirteen weeks.
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nReferences:
n1. HHS Publication, 5th ed., 2007. Biosafety in Microbiological and Biomedical Laboratories. Available http://www.cdc.gov/biosafety/publications/bmbl5/BMBL5
n2. Approved Guideline – Procedures for the Handling and Processing of Blood Specimens, H18-A3. 2004. Clinical and Laboratory Standards Institute.
n3. Kricka L. Interferences in immunoassays – still a threat. Clin Chem 2000; 46: 1037–1038.

產(chǎn)品描述: The PAPP-A enzyme linked immunosorbent assay (ELISA) kit provides materials for the quantitative measurement of PAPP-A in serum and other biological fluids.

其他: Ansh labs是開發(fā)和生產(chǎn)免疫檢測試劑盒和定制生物技術(shù)檢測產(chǎn)領(lǐng)創(chuàng)者，總部位于美國休斯敦，公司產(chǎn)品遍及全球80多個國家。公司于2011年成立，核心團隊來自于Diagnostic system laboratory，專注于女性健康和激素檢測領(lǐng)域近40年，擁有全球領(lǐng)先的核心技術(shù)，以及多年經(jīng)驗生物技術(shù)研發(fā)經(jīng)驗的科學(xué)家團隊，產(chǎn)品覆蓋生殖健康，高危妊娠，腫瘤，糖尿病等多個疾病領(lǐng)域，圍繞最新的免疫分析技術(shù)，多種蛋白和單克隆抗體，如AMH，BMP-15, Follistatin, GDF-9, IGF-I, IGF-II, IGFBP-2, IGFBP-3, IGFBP-4, IGFBP-5, Inhibin Alpha, Inhibin ?A, Inhibin ?B, MBP, PAPP-A, PAPP-A2 and Vitamin D.等幾十余種試劑產(chǎn)品，也同時涵蓋小鼠，大鼠，狗，羊，牛等靈長類多個物種的獨特的物種特異性的試劑。 Ansh labs 坐落于美國德克薩斯州，是目前世界上唯一能提供TGF-β超家族所有成員的檢測公司，也是最早專注激素類產(chǎn)品研究和新型免疫檢測技術(shù)的先驅(qū)者。優(yōu)勢產(chǎn)品涉及TGF-β super family、AMH/抑制素B(human/animal)、full panel IGFs、以及最完整的胰高血糖素系列。