- 中文名稱
PAPP-A2 ELISA
- 英文名字
- PAPP-A2 ELISA
- 供應(yīng)商
- Ansh Labs
- 產(chǎn)品貨號(hào)
- AL-109
- 產(chǎn)品報(bào)價(jià)
- ¥詢價(jià)/96wellmicrotiter

- 產(chǎn)品說明書
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- 購買方式
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- 產(chǎn)品新聞

- 背景資料
- Pregnancy associated plasma protein-A2 (PAPP-A2) is a novel metalloproteinase identified as a homolog of PAPP-A in the metzincin superfamily of pappalysins1-8. PAPP-A2 shares 46% sequence identity with PAPP-A3. PAPP-A2 is a noncovalently linked dimer of two 220-kDa subunits. It exhibits robust proteolytic activity against IGFBP-5 and possibly also IGFBP-3 3, 8. PAPP-A2 is expressed in a wide range of tissues and is abundant in placental syncytiotrophoblasts and the pregnant uterus3. The physiological importance of PAPP-A2 is not known.
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nReferences:
n1. Bulut I, Coskun A, Ciftci A et al. Relationship between Pregnancy-associated plasma protein A and lung cancer. The American Journal of the Medical sciences. April 2009; 337 (4): 241-244
n2. Schindler AM and Bischof B. Histochemical localization of pregnancy associated plasma protein-A in fetal, infant, and adult organs and camparison between sntisera. Gynecol Obstet Invest 1984; 18: 88-94.
n3. Overgaard MT, Oxvig C, Christiansen M , et al. Messenger ribonucleic acid levels of pregnancy-associated plasma protein-A and the preform of eosinophil major basic protein: expression in human reproductive and nonreproductive tissue. Biol Reprod 1999; 61:1083-1089.
n4. Fialova L, Kalousova M, Soukupova J, et. al. Relationship of pregnancy associated plasma protein A to renal function and dialysis modalities. Kidney Blood Press Res 2004; 27: 88-95.
n5. Coskum A, Balbay O, Duran S et al. Pregnancy-associated plasma protein A and asthama. Adv Ther 2007; 24: 362-367.
n6. Coskum A, Duran S, Apaydin S, et al. Pregnancy-associated plasma protein A: evaluation of a new biomarker in renal transplanted patients. Transplant Proc 2007; 39:3072-3076.
n7. Bayes-Genis A, Conover CA, Overgaard MT, et al. Pregnancy-associated plasma protein A as a marker of acute coronary syndromes. N Engl J Med 2001; 345: 1022-1029.
n8. Overgaard MT, Boldt HB, Laursen LS, Sottrup-Jensen L, Conover CA, Oxvig C. Pregnancy-associated plasma protein-A2 (PAPP-A2), a novel insulin-like growth factor-binding protein-5 proteinase. J Biol Chem 2001; 276:21849-21853.
n9. HHS Publication, 5th ed., 2007. Biosafety in Microbiological and Biomedical Laboratories. Available http://www.cdc.gov/biosafety/publications/bmbl5/BMBL5
n10. DHHS (NIOSH) Publication No. 78–127, August 1976. Current Intelligence Bulletin 13 - Explosive Azide Hazard. Available http:// www.cdc.gov/niosh.
n11. Approved Guideline – Procedures for the Handling and Processing of Blood Specimens, H18-A3. 2004. Clinical and Laboratory Standards Institute.
n12. Kricka L. Interferences in immunoassays – still a threat. Clin Chem 2000; 46: 1037–1038.
- 產(chǎn)品描述
- The PAPP-A2 enzyme linked immunosorbent assay (ELISA) kit provides materials for the quantitative measurement of PAPP-A2 in human serum and other biological fluids.
- 產(chǎn)品特點(diǎn)
- 保存建議
- Store at 2 to 8°C until expiration date.
- 其他
- Ansh labs是開發(fā)和生產(chǎn)免疫檢測試劑盒和定制生物技術(shù)檢測產(chǎn)領(lǐng)創(chuàng)者,總部位于美國休斯敦,公司產(chǎn)品遍及全球80多個(gè)國家。公司于2011年成立,核心團(tuán)隊(duì)來自于Diagnostic system laboratory,專注于女性健康和激素檢測領(lǐng)域近40年,擁有全球領(lǐng)先的核心技術(shù), 以及多年經(jīng)驗(yàn)生物技術(shù)研發(fā)經(jīng)驗(yàn)的科學(xué)家團(tuán)隊(duì),產(chǎn)品覆蓋生殖健康,高危妊娠,腫瘤,糖尿病等多個(gè)疾病領(lǐng)域,圍繞最新的免疫分析技術(shù),多種蛋白和單克隆抗體,如AMH,BMP-15, Follistatin, GDF-9, IGF-I, IGF-II, IGFBP-2, IGFBP-3, IGFBP-4, IGFBP-5, Inhibin Alpha, Inhibin ?A, Inhibin ?B, MBP, PAPP-A, PAPP-A2 and Vitamin D.等幾十余種試劑產(chǎn)品,也同時(shí)涵蓋小鼠,大鼠,狗,羊,牛等靈長類多個(gè)物種的獨(dú)特的物種特異性的試劑。
Ansh labs 坐落于美國德克薩斯州,是目前世界上唯一能提供TGF-β超家族所有成員的檢測公司,也是最早專注激素類產(chǎn)品研究和新型免疫檢測技術(shù)的先驅(qū)者。優(yōu)勢產(chǎn)品涉及TGF-β super family、AMH/抑制素B(human/animal)、full panel IGFs、以及最完整的胰高血糖素系列。
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