- 中文名稱
主要胰高血糖素前段片段 (MPGF) ELISA
- 英文名字
- Major Proglucagon Fragment (MPGF) ELISA
- 供應(yīng)商
- Ansh Labs
- 產(chǎn)品貨號(hào)
- AL-175
- 產(chǎn)品報(bào)價(jià)
- ¥詢價(jià)/96wellmicrotiter

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- 購買方式
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- 產(chǎn)品新聞

- 背景資料
- Major Proglucagon Fragment (MPGF) is an 86-amino acid hormone secreted from the pancreas1-3. MPGF is identified as the Carboxy terminal portion of proglucagon that contains two glucagon-related sequences. The MPGF sequence is highly conserved among mammals. Tissue specific processing of proglucagon in the pancreas releases MPGF. Intestinal processing of MPGF releases the Glucagon-Like Peptides 1 and 2 (GLP-1 and GLP-2)1-5. Measuring the circulating levels of MPGF will help in understanding the defective or abnormal metabolic pathways leading to diabetes and obesity. This kit is designed to measure MPGF.
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nReferences:
n1. Müller et al., (2017) The New Biology and Pharmacology of Glucagon. Physiol Rev 97: 721–766.
n2. Drucker DJ, Habener JF, Holst JJ Discovery, characterization, and clinical development of the glucagon-like peptides (2017) J Clin Invest. 127(12):4217-4227.
n3. Bonic A, Mackin RB (2003) Expression, purification, and PC1-mediated processing of human proglucagon, glicentin, and major proglucagon fragment. Protein Expr Purif 28:15–24.
n4. Amato A, Baldassano and Flavia Mulè. GLP2: an underestimated signal for improving glycaemic control and insulin sensitivity. Journal of Endocrinology (2016) 229, R57–R66
n5. Baldassano S, Amato A, Rappa F, Cappello F & Mulè F (2016b) Influence of endogenous glucagon like peptide-2 on lipid disorders in mice fed a high fat diet. Endocrine Research.
nVol. 41, Iss. 4.
n6. HHS Publication, 5th ed., 2007. Biosafety in Microbiological and Biomedical Laboratories. Available http://www.cdc.gov/biosafety/publications/bmbl5/BMBL5
n7. DHHS (NIOSH) Publication No. 78–127, August 1976. Current Intelligence Bulletin 13 - Explosive Azide Hazard. Available: http://www.cdc.gov/niosh.
n8. Kricka L. Interferences in immunoassays – still a threat. Clin Chem 2000; 46: 1037–1038.
- 產(chǎn)品描述
- The Major Proglucagon Fragment (MPGF) enzyme linked immunosorbent assay (ELISA) kit provides materials for the quantitative measurement of MPGF in EDTA plasma and other biological fluids.
- 產(chǎn)品特點(diǎn)
- 保存建議
- Store at 2 to 8°C until expiration date.
- 其他
- Ansh labs是開發(fā)和生產(chǎn)免疫檢測試劑盒和定制生物技術(shù)檢測產(chǎn)領(lǐng)創(chuàng)者,總部位于美國休斯敦,公司產(chǎn)品遍及全球80多個(gè)國家。公司于2011年成立,核心團(tuán)隊(duì)來自于Diagnostic system laboratory,專注于女性健康和激素檢測領(lǐng)域近40年,擁有全球領(lǐng)先的核心技術(shù), 以及多年經(jīng)驗(yàn)生物技術(shù)研發(fā)經(jīng)驗(yàn)的科學(xué)家團(tuán)隊(duì),產(chǎn)品覆蓋生殖健康,高危妊娠,腫瘤,糖尿病等多個(gè)疾病領(lǐng)域,圍繞最新的免疫分析技術(shù),多種蛋白和單克隆抗體,如AMH,BMP-15, Follistatin, GDF-9, IGF-I, IGF-II, IGFBP-2, IGFBP-3, IGFBP-4, IGFBP-5, Inhibin Alpha, Inhibin ?A, Inhibin ?B, MBP, PAPP-A, PAPP-A2 and Vitamin D.等幾十余種試劑產(chǎn)品,也同時(shí)涵蓋小鼠,大鼠,狗,羊,牛等靈長類多個(gè)物種的獨(dú)特的物種特異性的試劑。
Ansh labs 坐落于美國德克薩斯州,是目前世界上唯一能提供TGF-β超家族所有成員的檢測公司,也是最早專注激素類產(chǎn)品研究和新型免疫檢測技術(shù)的先驅(qū)者。優(yōu)勢產(chǎn)品涉及TGF-β super family、AMH/抑制素B(human/animal)、full panel IGFs、以及最完整的胰高血糖素系列。
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該頁面的中文產(chǎn)品信息的翻譯,僅供參考。準(zhǔn)確的產(chǎn)品信息請(qǐng)以廠家的英文說明書為準(zhǔn)。下單前,請(qǐng)瀏覽說明書確認(rèn)。
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