GDF-9 ELISA-GDF-9 ELISA代理/參數(shù)/廠家-ELISA試劑盒-艾美捷科技有限公司

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中文名稱: GDF-9 ELISA

英文名字: GDF-9 ELISA

供應(yīng)商: Ansh Labs

產(chǎn)品貨號: AL-176

產(chǎn)品報價: ￥詢價/96wellmicrotiter

產(chǎn)品說明書: 點擊查看

購買方式: 90%產(chǎn)品中國有現(xiàn)貨庫存。銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金，在線支付寶及網(wǎng)銀支付，或直接與我們電話聯(lián)系400-6800-868

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背景資料: BMP-15 and GDF-9 are synthesized as 249-295 amino acid N-terminal prodomains and 125-139 amino acid mature domains. The mature domains of GDF-9 and BMP-15 form 40 kDa and 34 kDa homodimers respectively and 37 kDa heterodimer 1,2. Growth Differentiation Factor 9 (GDF9) and Bone Morphogenic Protein 9 (BMP15) are oocyte secreted factors and play key roles in promoting follicle growth, maturation and oocyte competence 1,3-5. However, the action of BMP15 and GDF9 varied with respect to the species of origin and the stages of follicle development. Oocyte competence is an intrinsic developmental potential that allows a mature oocyte to become fertilized and develop to an embryo. Oocyte competence is achieved by long course of molecular, biochemical and morphological changes4. Recent study suggests AMH production is regulated by oocyte-secreted factors in primary human cumulus cells and the combination of GDF9 + BMP15 potently stimulates AMH expression6. Altered level and activity of GDF9 is implicated in premature ovarian failure and polycystic ovarian syndrome, implicating GDF9 in the etiology of these conditions 7-9.
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nReferences:
n1. Proc Natl Acad Sci U S A. 2013 Feb;110(8): E776-85.
n2. Endocrinology. 2012 Mar;153(3):1509-18.
n3. J Biol Chem. 2015 Sep;290(39):24007-20.
n4. Reproduction. 2005 Apr;129(4):473-80.
n5. Reproduction. 2017 Dec;154(6):745-753
n6. Dev Biol. 2006 Aug 15;296(2):514-21.
n7. J Assist Reprod Genet. 2012 Oct;29(10):1057-65.
n8. J Clin Endocrinol Metab. 2016 Dec;101(12):4541-4550.
n9. J Clin Endocrinol Metab. 2014 Apr;99(4): E615-24.

產(chǎn)品描述: The GDF-9 enzyme linked immunosorbent assay (ELISA) kit provides materials?for the quantitative measurement of GDF-9 in human serum and other?biological fluids.

產(chǎn)品特點

保存建議: Store at 2 to 8°C until expiration date.

其他: Ansh labs是開發(fā)和生產(chǎn)免疫檢測試劑盒和定制生物技術(shù)檢測產(chǎn)領(lǐng)創(chuàng)者，總部位于美國休斯敦，公司產(chǎn)品遍及全球80多個國家。公司于2011年成立，核心團(tuán)隊來自于Diagnostic system laboratory，專注于女性健康和激素檢測領(lǐng)域近40年，擁有全球領(lǐng)先的核心技術(shù)，以及多年經(jīng)驗生物技術(shù)研發(fā)經(jīng)驗的科學(xué)家團(tuán)隊，產(chǎn)品覆蓋生殖健康，高危妊娠，腫瘤，糖尿病等多個疾病領(lǐng)域，圍繞最新的免疫分析技術(shù)，多種蛋白和單克隆抗體，如AMH，BMP-15, Follistatin, GDF-9, IGF-I, IGF-II, IGFBP-2, IGFBP-3, IGFBP-4, IGFBP-5, Inhibin Alpha, Inhibin ?A, Inhibin ?B, MBP, PAPP-A, PAPP-A2 and Vitamin D.等幾十余種試劑產(chǎn)品，也同時涵蓋小鼠，大鼠，狗，羊，牛等靈長類多個物種的獨特的物種特異性的試劑。 Ansh labs 坐落于美國德克薩斯州，是目前世界上唯一能提供TGF-β超家族所有成員的檢測公司，也是最早專注激素類產(chǎn)品研究和新型免疫檢測技術(shù)的先驅(qū)者。優(yōu)勢產(chǎn)品涉及TGF-β super family、AMH/抑制素B(human/animal)、full panel IGFs、以及最完整的胰高血糖素系列。