BMP-15 ELISA-BMP-15 ELISA代理/參數(shù)/廠家-ELISA試劑盒-艾美捷科技有限公司

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背景資料: Growth Differentiation Factor 9 (GDF-9) and its closest paralog Bone Morphogenetic Protein 15 (BMP15; also known as GDF-9B) are oocyte-specific growth factors and distinguish themselves from granulosa cell-derived markers of ovarian function (such as AMH, inhibin A, inhibin B, E2) and thus may provide a more direct assessment of oocyte function competence. The mature peptide portions of GDF-9 and BMP-15 can form non-covalent bioactive homo- and heterodimers, but no methods have been available for measuring these different forms in biological fluids. BMP-15 and GDF-9 are synthesized as precursors with 249-295 amino acid N-terminal pro-peptides and 125-139 amino acid mature domains. GDF-9 and BMP-15 form 40 kDa and 34 kDa homodimers and 37 kDa heterodimers. Recent evidence shows that the GDF-9:BMP-15 is a highly active GDF-9-like super agonist being up to 1000-fold more potent than GDF-9 itself. GDF-9:BMP-15 appears to be the biologically most relevant form of the dimers.

產(chǎn)品描述: The BMP-15 Enzyme-Linked Immunosorbent Assay (ELISA) kit provides materials for the quantitative measurement of BMP-15 in follicular fluid.

其他: Ansh labs是開發(fā)和生產(chǎn)免疫檢測試劑盒和定制生物技術(shù)檢測產(chǎn)領(lǐng)創(chuàng)者，總部位于美國休斯敦，公司產(chǎn)品遍及全球80多個國家。公司于2011年成立，核心團隊來自于Diagnostic system laboratory，專注于女性健康和激素檢測領(lǐng)域近40年，擁有全球領(lǐng)先的核心技術(shù)，以及多年經(jīng)驗生物技術(shù)研發(fā)經(jīng)驗的科學(xué)家團隊，產(chǎn)品覆蓋生殖健康，高危妊娠，腫瘤，糖尿病等多個疾病領(lǐng)域，圍繞最新的免疫分析技術(shù)，多種蛋白和單克隆抗體，如AMH，BMP-15, Follistatin, GDF-9, IGF-I, IGF-II, IGFBP-2, IGFBP-3, IGFBP-4, IGFBP-5, Inhibin Alpha, Inhibin ?A, Inhibin ?B, MBP, PAPP-A, PAPP-A2 and Vitamin D.等幾十余種試劑產(chǎn)品，也同時涵蓋小鼠，大鼠，狗，羊，牛等靈長類多個物種的獨特的物種特異性的試劑。 Ansh labs 坐落于美國德克薩斯州，是目前世界上唯一能提供TGF-β超家族所有成員的檢測公司，也是最早專注激素類產(chǎn)品研究和新型免疫檢測技術(shù)的先驅(qū)者。優(yōu)勢產(chǎn)品涉及TGF-β super family、AMH/抑制素B(human/animal)、full panel IGFs、以及最完整的胰高血糖素系列。