SBDS is part of an extremely preserved protein family which exists from archaea to vertebrates and plants. SBDS protein functions in RNA metabolism and has a role in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Shwachman-Diamond syndrome is a rare autosomal recessive disorder produced by mutations in the SBDS gene.
應(yīng)用類型
【SBDS】小鼠抗人許氏癥SBDS抗體Mouse Anti Human Shwachman-Bodian-Diamond Syndrome該產(chǎn)品的應(yīng)用類型查閱產(chǎn)品說明書。
免疫原
Anti-human SBDS mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human SBDS amino acids 1-250 purified from E. coli.