mAB-M |小鼠抗人類Abeta蛋白（3-10）區(qū)域，寡聚物特異性-mAB-M | Mouse anti-human Abeta protein (3-10) region, oligomer-specific (clone 2D10,F6)代理/參數(shù)/廠家-植物抗體-艾美捷科技有限公司

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英文名字: mAB-M | Mouse anti-human Abeta protein (3-10) region, oligomer-specific (clone 2D10,F6)

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背景資料: Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the growing population of elderly people. A hallmark of AD is the accumulation of plaques in the brain of AD patients. The plaques predominantly consist of aggregates of amyloid-beta (Abeta), a peptide of 39-42 amino acids generated in vivo by specific, proteolytic cleavage of the amyloid precursor protein. Recent findings however suggest that smaller oligomeric forms of Abeta, formed in parallel to the amyloid plaques, excert the predominant tissue damaging effect.Specific identification of the oligomeric forms is as a consequence of great interest. Based on a recently published technique a highly oligomer-specific antibody (mAB-M), targeting Abeta oligomers while omitting reactivity towards the monomeric and fibrillar counterpart, has been developed.

免疫原: synthetic peptide chosen from human Abeta protein (3-10) pregion, oligomer specific

其他: Agrisera公司提供1000種用于植物和藻類細(xì)胞生物學(xué)研究的一抗，2000多種二抗。Agrisera公司提供的植物領(lǐng)域的抗體涵蓋擬南芥、萊茵衣藻、藍(lán)藻、松柏類、硅藻、大豆、大麥、蒺藜苜蓿、煙草、稻、菜豆、小立碗蘚、楊樹、豌豆、番茄、馬鈴薯、菠菜、小麥、玉米、葡萄等多個(gè)物種，此外還有水生生物類（藻類、魚）抗體，細(xì)菌、昆蟲、真菌抗體。針對(duì)植物蛋白質(zhì)的保守氨基酸序列，Agirsera還獨(dú)家開發(fā)了數(shù)十種通用抗體（global antibodies），這類抗體幾乎可以與所有的高等植物及藻類產(chǎn)生免疫反應(yīng)，可為研究人員提供極為方便的選擇。