中文名稱

6-FAM-吡可酰疊氮化物

英文名字

6-FAM-Picolyl-Azide

供應(yīng)商

Baseclick

產(chǎn)品貨號

BCFA-247-5

產(chǎn)品報(bào)價(jià)

￥詢價(jià)/5mg

產(chǎn)品說明書

點(diǎn)擊查看

購買方式

銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金，在線支付寶及網(wǎng)銀支付，或直接與我們電話聯(lián)系400-6800-868

產(chǎn)品新聞

背景資料

6-FAM-吡可酰疊氮化物(6-FAM-Picolyl-Azide)背景資料,請查看該產(chǎn)品的使用說明書

產(chǎn)品描述

This special green-fluorescent dye (6-FAM picolyl azide)[1] enables advanced click reaction kinetics due to the usage of a picolyl-azide. This structure can complex copper and, therefore, the dye is already connected to its catalyst for the efficient click reaction. One benefit is that reducing copper concentration allows click reaction with sensitive reactants. Picolyl azides enhance the reaction kinetics so much that it is possible to have a picolyl structure that reacts selectively with an alkyne even when other azides are present.[2]This enables among other things the usage of less amount of copper in the click reaction mixture without any effect on the great reaction efficiency achieving the same reaction yields. This effect can be crucial e.g. when copper sensitive enzyme or biomolecules shall be labeled. Once attached to a biomolecule via click chemistry (CuAAC, copper catalyzed alkyne-azide cycloaddition) fluorescence microscopy detection can be performed similar to standard dyes. Due to the spectral properties the 6-FAM picolyl dye can be used as AF488 alternative and FITC alternative.

產(chǎn)品形式

Solid

保存建議

-20 °C, 避光

其他

Baseclick于2008成立于2008年德國慕尼黑，BaseClick的核心競爭力源于其專有的銅催化疊氮-炔環(huán)加成（CuAAC）點(diǎn)擊化學(xué)技術(shù)。該技術(shù)由2001年諾貝爾化學(xué)獎(jiǎng)得主Barry Sharpless教授發(fā)明，BaseClick擁有在核酸領(lǐng)域應(yīng)用該技術(shù)的全球獨(dú)家許可。相比傳統(tǒng)方法，點(diǎn)擊化學(xué)具有反應(yīng)迅速、條件溫和、產(chǎn)率高、選擇性強(qiáng)等顯著優(yōu)勢，可實(shí)現(xiàn)從小分子寡核苷酸到大基因片段的高效、精準(zhǔn)功能化修飾。目前的應(yīng)用領(lǐng)域包括：核酸標(biāo)記技術(shù)、Edu細(xì)胞增殖試驗(yàn)，PCR標(biāo)記試劑盒，F(xiàn)ISH探針，（高度）修飾的寡核苷酸等等，Baseclick跟Thermo Fisher，Roche，Merck，abcam，BD Bioscience等諸多知名品牌建立了合作關(guān)系。

注意

該頁面的中文產(chǎn)品信息的翻譯，僅供參考。準(zhǔn)確的產(chǎn)品信息請以廠家的英文說明書為準(zhǔn)。下單前，請瀏覽說明書確認(rèn)。

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