TrkA ELISA試劑盒（2個板）-Rat TrkA ELISA Kit (2 plates)代理/參數(shù)/廠家-ELISA試劑盒-艾美捷科技有限公司

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背景資料: TrkA is a member of the neurotrophic tyrosine kinase receptor family. It is a membrane-bound receptor that upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. TrkA is required for high-affinity binding to nerve growth factor (NGF), neurotrophin-3 and neurotrophin-4/5 but not brain-derived neurotrophic factor (BDNF). TrkA leads to cell differentiations and may play a role in specifying sensory neuron subtypes. It has a crucial role in the development and function of the nociceptive reception system as well as establishment of thermal regulation via sweating.

產品描述: The rat TrkA Kit is a sandwich ELISA. The capture antibody is a polyclonal rat TrkA antibody pre-coated onto the 96-well strip plates provided in the kit. Test samples and standards of known TrkA concentration are added to these wells and allowed to complex with the bound TrkA antibody. A biotinylated rat polyclonal antibody is then added. This detection antibody binds to the antigen thus completing the sandwich. After washing, an enzyme Avidin-Biotin-Peroxidase complex (ABC) is added which binds to the second antibody. The peroxidase substrate TMB is added to induce a coloured reaction product. The intensity of this coloured product is directly proportional to the concentration of TrkA present in the samples. The purpose of this kit is the in-vitro quantitative determination of rat TrkA in samples such as sera, plasma, tissue lysates and cell culture supernates. This kit has been configured for research use only and is not to be used in diagnostic or clinical procedures.

產品特點: 靈敏度:156 pg/mL - 10000 pg/mL。此外該ELIAS試劑盒包含：2 x 96孔預包被條孔板（可拆卸）, 蛋白質標準品，檢測試劑，底物緩沖液，以及詳細的實驗方案。

其他: Biosensis專注于神經科學領域的抗體和試劑的開發(fā)，特別是神經營養(yǎng)因子和神經營養(yǎng)因子受體。近30年來，Biosensis一直是該領域的全球領航者和OEM供應商。除神經營養(yǎng)因子，我們的神經科學產品組合還被廣泛用于神經退行性疾病、神經發(fā)育和神經代謝的研究。重點研究領域包括阿爾茨海默氏癥（AD）、帕金森氏癥（PD）和肌萎縮側索硬化（ALS）疾病，以及自噬和代謝應激障礙，包括肥胖、代謝綜合征的研究、神經免疫學和炎癥。Biosensis的產品系列不僅包括持續(xù)增長的神經科學研究抗體系列，還包括200多種定量研究ELISAs試劑盒（1板或2板，自由選擇），組織染色（退化神經元染色試劑盒、病理髓鞘染色試劑盒、淀粉樣斑塊染色試劑等）和細胞可視化試劑（染色）以及針對神經科學和細胞疾病研究的純化的蛋白質。我們的抗體和試劑已被廣泛應用于各種技術，包括蛋白質印跡，免疫組織化學，流式分析，共聚焦顯微鏡實時成像，生物抑制和細胞培養(yǎng)以及克隆。