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ELISA試劑盒
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中文名稱

B型腦鈉肽 EIA試劑盒

英文名字
BNP Fragment EIA Kit
供應(yīng)商
Biomedica Immunoassays
產(chǎn)品貨號(hào)
BI-20852W
產(chǎn)品報(bào)價(jià)
¥12x8tests
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背景資料
The natriuretic peptides are members of a family of structurally similar but genetically distinct peptide hormones, consisting of atrial-, brain-, and C-type (ANP, BNP, and CNP, respectively). ANP and BNP preferentially bind to a membrane-bound guanylyl cyclase (GC) receptor called GC-A or NPR1, whereas CNP is the physiological ligand for GC-B (NPR2). The natriuretic peptides play an important role in the regulation of cardiovascular and renal homeostasis and in the regulation of fatty acid metabolism and body weight.

BNP is mainly expressed by ventricular myocardium in response to volume overload and increased filling pressure. BNP has a cleavable signal sequence. Mature BNP consists of 108 amino acids (proBNP or BNP-108), and undergoes cleavage resulting in physiologically active BNP-32 and additional C-terminal fragments (cf. http://www.uniprot.org/uniprot/P16860#PRO_0000001532), along with a physiologically inactive N-terminal peptide comprising amino acids 1-76 (NT-proBNP), which is further degraded proteolytically.
產(chǎn)品描述
Method Competitive enzyme immunoassay (EIA), HRP/TMB, 12×8-well detachable strips Sample type Serum, EDTA plasma, hepar?n plasma, citrate plasma Product volume 30 μl / well Assay time Overnight (18 – 25 h) / 20 min Sensitivity 171 pmol/l (=1449 pg/ml) Standard range 0 – 6,400 pmol/l (0 – 54,237 pg/ml) Conversion factor 1 pmol/l = 8.475 pg/ml (MW: 8.475 kDa) Specificity Endogenous and recombinant human NT-proBNP. Precision In-between-run (n=8): ≤ 7 % CV Within-run (n=3): ≤ 3 % CV Cross-reactivity The assay does not cross react with rat, mouse, dog, or cat samples.
產(chǎn)品特點(diǎn)
保存建議
+4°C
其他
Biomedica Immunoassay(bmgrp)公司成立于1988年, 總部位于奧地利維也納,主要致力于研究、開發(fā)和生產(chǎn)基于ELISA方法用于臨床前研究相關(guān)標(biāo)記物檢測(cè)的工具。迄今為止Biomedica Immunoassay公司在心血管檢測(cè)及骨代謝檢測(cè)領(lǐng)域開發(fā)了一系列特色ELISA檢測(cè)試劑盒,Biomedica Immunoassay的生產(chǎn)過程符合GMP/GLP指南,并符合ISO 9001:2015管理體系,有CE認(rèn)證。Biomedica Immunoassay的產(chǎn)品根據(jù)FDA, EMEA和ICH指南進(jìn)行驗(yàn)證,并具有驗(yàn)證報(bào)告。
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