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ELISA試劑盒
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中文名稱(chēng)

包柔氏螺旋體菌IgG Elisa試劑盒

英文名字
Borrelien IgG ELISA Kit
供應(yīng)商
Biomedica Immunoassays
產(chǎn)品貨號(hào)
BI-21032
產(chǎn)品報(bào)價(jià)
￥12x8tests
產(chǎn)品說(shuō)明書(shū)
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產(chǎn)品新聞
背景資料
Lyme borreliosis is a bacterial infection caused by the spirochete Borrelia Burgdorferi, Borrelia Afzelii and Borrelia Garinii and is the most vector-transmitted human disease in Europe. The spirochetal bacteria were first described and isolated in 1981 by Willi Burgdorfer in the tick Ixodes dammini in Montana (USA). The infection with Borrelia is characterized by a variety of clinical symptoms and can be divided into 3 stages:

Stage 1, early dermatitis, appearing days or weeks after the infection. Clinical: erythema migrans.
Stage 2, early disseminated infection, appears weeks to months after infection. Clinical: lymphocytic meningoradiculitis (Bannwarth's syndrome), neuroborreliosis.
Stage 3, late disseminated infection, occurring up to years after infection. Clinical: chronic progressive encephalomyelitis, acrodermatitis chronica atrophicans (ACA), chronic arthritis.
Antibiotic therapy is indicated in all stages of the disease. It shortens disease duration significantly, when instituted in stage 1. Diagnosis of the bacterial infection relies on the detection of specific IgG antibodies against Borrelia.

To ensure diagnostic specificity, the Borrelia IgG ELISA microwell strips are coated with the following Borellia-specific recombinant antigens:

p18: B. afzelii (pKo)
p21 = OspC (outer surface protein C): B. burgdorferi s.s. (B31), B. garinii (20047)
p100: B. afzelii (pKo)
VlsE: fusion protein of different genospecies
Many features of later infection are not specific to Lyme Borreliosis and occur in other conditions. The diagnosis of Lyme Borreliosis should be made only after careful evaluation of the patient′s clinical history, physical findings, laboratory evidence and exposure risk evaluation
產(chǎn)品描述
Method Indirect ELISA, HRP/TMB, 12×8-well detachable strips Sample type Serum, plasma and CSF Sample volume 10 μl / sample (serum and plasma), 100 μl / sample (CSF) Assay time 1 h / 30 min / 15 min Standard range 0 – 30 BBU/ml (Biomedica Borrelia Units) Sensitivity 100% (serum) 87.5% (CSF) Specificity Endogenous and recombinant human anti-Borrelia IgG (B. burgdoreri ss, B. afzelii, B. garnii, B. bavariensis)
產(chǎn)品特點(diǎn)
保存建議
+4°C
其他
Biomedica Immunoassay(bmgrp)公司成立于1988年, 總部位于奧地利維也納，主要致力于研究、開(kāi)發(fā)和生產(chǎn)基于ELISA方法用于臨床前研究相關(guān)標(biāo)記物檢測(cè)的工具。迄今為止Biomedica Immunoassay公司在心血管檢測(cè)及骨代謝檢測(cè)領(lǐng)域開(kāi)發(fā)了一系列特色ELISA檢測(cè)試劑盒，Biomedica Immunoassay的生產(chǎn)過(guò)程符合GMP/GLP指南，并符合ISO 9001:2015管理體系，有CE認(rèn)證。Biomedica Immunoassay的產(chǎn)品根據(jù)FDA， EMEA和ICH指南進(jìn)行驗(yàn)證，并具有驗(yàn)證報(bào)告。
注意
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