包柔氏螺旋體菌IgM Elisa試劑盒-Borrelien IgM ELISA Kit代理/參數(shù)/廠家-ELISA試劑盒-艾美捷科技有限公司

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中文名稱: 包柔氏螺旋體菌IgM Elisa試劑盒

英文名字: Borrelien IgM ELISA Kit

供應(yīng)商: Biomedica Immunoassays

產(chǎn)品貨號: BI-21042

產(chǎn)品報價: ￥12x8tests

產(chǎn)品說明書: 點擊查看

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背景資料: Lyme borreliosis is a bacterial infection caused by the spirochete Borrelia Burgdorferi, Borrelia Afzelii and Borrelia Garinii and is the most vector-transmitted human disease in Europe. The spirochetal bacteria were first described and isolated in 1981 by Willi Burgdorfer in the tick Ixodes dammini in Montana (USA). The infection with Borrelia is characterized by a variety of clinical symptoms and can be divided into 3 stages:

Stage 1, early dermatitis, appearing days or weeks after the infection. Clinical: erythema migrans.
Stage 2, early disseminated infection, appears weeks to months after infection. Clinical: lymphocytic meningoradiculitis (Bannwarth's syndrome), neuroborreliosis.
Stage 3, late disseminated infection, occurring up to years after infection. Clinical: chronic progressive encephalomyelitis, acrodermatitis chronica atrophicans (ACA), chronic arthritis.
Antibiotic therapy is indicated in all stages of the disease. It shortens disease duration significantly, when instituted in stage 1. Diagnosis of the bacterial infection relies on the detection of specific IgM antibodies against Borrelia.

To ensure diagnostic specificity, the Borrelia IgM ELISA microwell strips are coated with the following Borellia-specific recombinant antigens:

p21 = OspC (outer surface protein C): B. afzellii (pKo), B. garinii (20047)

p41/I = (inner part of flagellin): B. bavariensis (pBi)

VIsE: fusion proteins of different Borrelia genospecies

Many features of later infection are not specific to Lyme Borreliosis and occur in other conditions. The diagnosis of Lyme Borreliosis should be made only after careful evaluation of the patient′s clinical history, physical findings, laboratory evidence and exposure risk evaluation.

產(chǎn)品描述: Method Indirect ELISA, HRP/TMB, 12×8-well detachable strips Sample type Serum, plasma and CSF Sample volume 10 μl / sample (serum and plasma), 100 μl / sample (CSF) Assay time 1 h / 30 min / 15 min Standard range 0 – 30 BBU/ml (Biomedica Borrelia Units) Sensitivity 100% (serum) 82% (CSF) Cross-reactivity The assay works with human samples only. Specificity Endogenous and recombinant human anti-Borrelia IgM (B. burgdoreri ss, B. afzelii, B. garnii, B. bavariensis)

產(chǎn)品特點

保存建議: +4°C

其他: Biomedica Immunoassay(bmgrp)公司成立于1988年, 總部位于奧地利維也納，主要致力于研究、開發(fā)和生產(chǎn)基于ELISA方法用于臨床前研究相關(guān)標記物檢測的工具。迄今為止Biomedica Immunoassay公司在心血管檢測及骨代謝檢測領(lǐng)域開發(fā)了一系列特色ELISA檢測試劑盒，Biomedica Immunoassay的生產(chǎn)過程符合GMP/GLP指南，并符合ISO 9001:2015管理體系，有CE認證。Biomedica Immunoassay的產(chǎn)品根據(jù)FDA， EMEA和ICH指南進行驗證，并具有驗證報告。