- 中文名稱
重組CNTF，人
- 英文名字
- RecombinantCNTF,Human
- 供應(yīng)商
- Bioworld
- 產(chǎn)品貨號(hào)
- BK0017
- 產(chǎn)品報(bào)價(jià)
- ￥詢價(jià)/10ug
- 產(chǎn)品說明書
- 點(diǎn)擊查看
- 購(gòu)買方式
- 銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金，在線支付寶及網(wǎng)銀支付，或直接與我們電話聯(lián)系400-6800-868
- 產(chǎn)品新聞
- 背景資料
- Ciliary Neurotrophic Factor (CNTF) is a cytokine belonging to the Interleukin 6 (IL-6) family, which also includes IL-6, Oncostatin M, Leukemia Inhibitory Factor (LIF), and Cardiotrophin-1. Structurally, CNTF resembles a four-helix bundle composition, similar to the other members of the IL-6 family. The receptor for CNTF is composed of three parts: a gp130-like subunit common in the IL-6 receptor family, a LIF Receptor β subunit, and a CNTF specific α receptor subunit. Upon binding to the CNTF, the β subunit of the CNTF receptor will undergo tyrosine phosphorylation, and activate the intracellular JAK/STAT pathway. The main function of CNTF in vivo is to promote the differentiation and survival of a variety of neurons and glial cells, including sympathetic precursor cells and spinal motor neurons.Recombinant human Ciliary Neurotrophic Factor (rhCNTF) produced in E. coli is a single non-glycosylated polypeptide chain containing 199 amino acids. A fully biologically active molecule, rhCNTF has a molecular mass of 22.8 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
- 序列
- AFT EHSPLTPHRR DLCSRSIWLA RKIRSDLTAL TESYVKHQGL NKNINLDSAD GMPVASTDQW SELTEAERLQ ENLQAYRTFH VLLARLLEDQ
QVHFTPTEGD FHQAIHTLLL QVAAFAYQIE ELMILLEYKI PRNEADGMPI NVGDGGLFEK KLWGLKVLQE LSQWTVRSIH DLRFISSHQT GIPARGSHYI
ANNKKM
- 來源宿主
- Escherichia coli.
- 溶解建議
- Reconstituted in ddH2O or PBS at 100 μg/ml.
- 保存建議
- Lyophilized recombinant human Ciliary Neurotrophic Factor (rhCNTF) remains stable up to 6 months at -80
- 其他
- Bioworld是專一服務(wù)于生命科學(xué)研究的專業(yè)技術(shù)型企業(yè)，Bioworld品牌創(chuàng)立以來?yè)碛?0000多種常規(guī)產(chǎn)品現(xiàn)貨，現(xiàn)有8000多種現(xiàn)貨抗體，以及其他IVD原料，蛋白等現(xiàn)貨產(chǎn)品。在細(xì)胞信號(hào)通路、免疫學(xué)、蛋白組學(xué)上擁有顯著優(yōu)勢(shì)，其抗體產(chǎn)品、生長(zhǎng)因子、IVD原料等為生命科學(xué)科研工作者提供了極大的便利
- 注意
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該頁(yè)面的中文產(chǎn)品信息的翻譯，僅供參考。準(zhǔn)確的產(chǎn)品信息請(qǐng)以廠家的英文說明書為準(zhǔn)。下單前，請(qǐng)瀏覽說明書確認(rèn)。
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