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中文名稱

重組EGF,大鼠

英文名字
RecombinantEGF,Rat
供應(yīng)商
Bioworld
產(chǎn)品貨號(hào)
BK0028
產(chǎn)品報(bào)價(jià)
¥詢價(jià)/100ug
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產(chǎn)品新聞
背景資料
Epidermal Growth Factor (EGF) is a cytokine with 53 amino acids, originally found in mouse submaxillary gland. EGF binds to EGF receptors, ErbB1 and B4, and causes them to be dimerized and phosphorylated. The dimerized and phosphorylated EGFR can bind to several intracellular targets, such as phospholipase Cγ and Ras-GTPase-acting protein, and achieve a series of cascade reactions. EGF is involved in the regulation of cell proliferation and differentiation, and is up-regulated during wound healing, accelerating reepitheliazation and increasing tensile strength. It also stimulates neurite outgrowth and increases the uptake of dopamine in the central nervous system. On the other hand, EGF is up-regulated in the glioma cancer, and related to the length of survivals of the patients.Recombinant rat Epidermal Growth Factor (rrEGF) produced in E.coli is a single non-glycosylated polypeptide chain containing 54 amino acids. A fully biologically active molecule, rrEGF has a molecular mass of 6.3 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
序列
MNSNTGCPP SYDGYCLNGG VCMYVESVDR YVCNCVIGYI GERCQHRDLR WWKLR
來(lái)源宿主
Escherichia coli.
溶解建議
Reconstituted in ddH2O at 100 μg/mL.
保存建議
Lyophilized recombinant rat Epidermal Growth Factor (rrEGF) remains stable up to 6 months at -80
其他
Bioworld是專一服務(wù)于生命科學(xué)研究的專業(yè)技術(shù)型企業(yè),Bioworld品牌創(chuàng)立以來(lái)?yè)碛?0000多種常規(guī)產(chǎn)品現(xiàn)貨,現(xiàn)有8000多種現(xiàn)貨抗體,以及其他IVD原料,蛋白等現(xiàn)貨產(chǎn)品。在細(xì)胞信號(hào)通路、免疫學(xué)、蛋白組學(xué)上擁有顯著優(yōu)勢(shì),其抗體產(chǎn)品、生長(zhǎng)因子、IVD原料等為生命科學(xué)科研工作者提供了極大的便利
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