- 中文名稱
重組LIF，人
- 英文名字
- RecombinantLIF,Human
- 供應(yīng)商
- Bioworld
- 產(chǎn)品貨號
- BK0121
- 產(chǎn)品報價
- ￥詢價/10ug
- 產(chǎn)品說明書
- 點(diǎn)擊查看
- 購買方式
- 銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金，在線支付寶及網(wǎng)銀支付，或直接與我們電話聯(lián)系400-6800-868
- 產(chǎn)品新聞
- 背景資料
- Leukemia Inhibitory Factor (LIF) is a pleiotropic cytokine belonging to the long four-helix bundle cytokine superfamily. LIF shares tertiary structure with several other cytokines, including Interleukin-6 (IL-6), Oncostatin M, ciliary neurotropic factor, and cardiotrophin-1, and their functions in vivo are also redundant to some extent. LIF can bind to the common receptor of IL-6 subfamily, gp130, and then recruit its own receptor LIF Receptor to form a ternary complex. The basal expression of LIF in vivo is low; and its expression is induced by pro-inflammatory factors, including lipopolysaccharide, IL-1, and IL-17, and inhibited by anti-inflammatory agents, including IL-4 and IL-13. The functions of LIF include proliferation of primordial germ cells, regulation in blastocyst implantation and early pregnancy, and maintenance of pluripotent embryonic stem cells.Recombinant human Leukemia Inhibitory Factor (rhLIF) produced in E.coli is a single non-glycosylated polypeptide chain containing 180 amino acids. A fully biologically active molecule, rhLIF has a molecular mass of 19.7 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
- 序列
- SPL PITPVNATCA IRHPCHNNLM NQIRSQLAQL NGSANALFIL YYTAQGEPFP NNLDKLCGPN VTDFPPFHAN GTEKAKLVEL YRIVVYLGTS LGNITRDQKI LNPSALSLHS KLNATADILR GLLSNVLCRL CSKYHVGHVD VTYGPDTSGK DVFQKKKLGC QLLGKYKQII AVLAQAF
- 來源宿主
- Escherichia coli.
- 溶解建議
- Reconstituted in ddH2O at 100 μg/mL.
- 保存建議
- Lyophilized recombinant human Leukemia Inhibitory Factor (rhLIF) remains stable up to 6 months at -80
- 其他
- Bioworld是專一服務(wù)于生命科學(xué)研究的專業(yè)技術(shù)型企業(yè)，Bioworld品牌創(chuàng)立以來擁有10000多種常規(guī)產(chǎn)品現(xiàn)貨，現(xiàn)有8000多種現(xiàn)貨抗體，以及其他IVD原料，蛋白等現(xiàn)貨產(chǎn)品。在細(xì)胞信號通路、免疫學(xué)、蛋白組學(xué)上擁有顯著優(yōu)勢，其抗體產(chǎn)品、生長因子、IVD原料等為生命科學(xué)科研工作者提供了極大的便利
- 注意
-
該頁面的中文產(chǎn)品信息的翻譯，僅供參考。準(zhǔn)確的產(chǎn)品信息請以廠家的英文說明書為準(zhǔn)。下單前，請瀏覽說明書確認(rèn)。
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