中文名稱(chēng)

重組LIF，小鼠

英文名字

RecombinantLIF,Mouse

供應(yīng)商

Bioworld

產(chǎn)品貨號(hào)

BK0122

產(chǎn)品報(bào)價(jià)

￥詢(xún)價(jià)/10ug

產(chǎn)品說(shuō)明書(shū)

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購(gòu)買(mǎi)方式

銀行轉(zhuǎn)賬、電匯、支票、現(xiàn)金，在線支付寶及網(wǎng)銀支付，或直接與我們電話聯(lián)系400-6800-868

產(chǎn)品新聞

背景資料

Leukemia Inhibitory Factor (LIF) is a pleiotropic cytokine belonging to the long four-helix bundle cytokine superfamily. LIF shares tertiary structure with several other cytokines, including Interleukin-6 (IL-6), Oncostatin M, ciliary neurotropic factor, and cardiotrophin-1, and their functions in vivo are also redundant to some extent. LIF can bind to the common receptor of IL-6 subfamily, gp130, and then recruit its own receptor LIF Receptor to form a ternary complex. The basal expression of LIF in vivo is low; and its expression is induced by pro-inflammatory factors, including lipopolysaccharide, IL-1, and IL-17, and inhibited by anti-inflammatory agents, including IL-4 and IL-13. The functions of LIF include proliferation of primordial germ cells, regulation in blastocyst implantation and early pregnancy, and maintenance of pluripotent embryonic stem cells.Recombinant mouse Leukemia Inhibitory Factor (rmLIF) produced in E.coli is a single non-glycosylated polypeptide chain containing 180 amino acids. A fully biologically active molecule, rmLIF has a molecular mass of 19.9 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.

序列

SPL PITPVNATCA IRHPCHGNLM NQIKNQLAQL NGSANALFIS YYTAQGEPFP NNVEKLCAPN MTDFPSFHGN GTEKTKLVEL YRMVAYLSAS LTNITRDQKV LNPTAVSLQV KLNATIDVMR GLLSNVLCRL CNKYRVGHVD VPPVPDHSDK EAFQRKKLGC QLLGTYKQVI SVVVQAF SPL PITPVNATCA IRHPCHGNLM NQIKNQLAQL NGSANALFIS YYTAQGEPFP NNVEKLCAPN MTDFPSFHGN GTEKTKLVEL YRMVAYLSAS LTNITRDQKV LNPTAVSLQV KLNATIDVMR GLLSNVLCRL CNKYRVGHVD VPPVPDHSDK EAFQRKKLGC QLLGTYKQVI SVVVQAF

來(lái)源宿主

Escherichia coli.

溶解建議

Reconstituted in ddH2O at 100 μg/mL.

保存建議

Lyophilized recombinant mouse Leukemia Inhibitory Factor (rmLIF) remains stable up to 6 months at -80

其他

Bioworld是專(zhuān)一服務(wù)于生命科學(xué)研究的專(zhuān)業(yè)技術(shù)型企業(yè)，Bioworld品牌創(chuàng)立以來(lái)?yè)碛?0000多種常規(guī)產(chǎn)品現(xiàn)貨，現(xiàn)有8000多種現(xiàn)貨抗體，以及其他IVD原料，蛋白等現(xiàn)貨產(chǎn)品。在細(xì)胞信號(hào)通路、免疫學(xué)、蛋白組學(xué)上擁有顯著優(yōu)勢(shì)，其抗體產(chǎn)品、生長(zhǎng)因子、IVD原料等為生命科學(xué)科研工作者提供了極大的便利

注意

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