- 中文名稱
重組MIP-5/CCL 15(92 aa),人
- 英文名字
- RecombinantMIP-5/CCL15(92aa),Human
- 供應(yīng)商
- Bioworld
- 產(chǎn)品貨號
- BK0140
- 產(chǎn)品報(bào)價(jià)
- ¥詢價(jià)/1mg

- 產(chǎn)品說明書
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- 購買方式
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- 產(chǎn)品新聞

- 背景資料
- Macrophage Inflammatory Protein-5 (MIP-5/CCL15) is a chemokine originally identified in the human hemofiltrate, thus it is also named Hemofiltrate CC Chemokine-2 (HCC-2). MIP-5 belongs to the CCL chemokine family, and its receptors are G-protein coupled receptors CCR1 and CCR3, with CCR1 being the major one. MIP-5 is mainly expressed in heart and skeletal muscle, and CCR1 is expressed on Th1 and Th2 cells in human cord blood lymphocytes. In vivo, MIP-5 promotes the accumulation of immature myeloid cells and the expansion of metastatic foci in the lever. MIP-5 contributes to severe asthma, sarcoidosis, and atherosclerosis;however, MIP-5 can also inhibit stem cell proliferation, implicating its therapeutic potential as an alternative to high dose chemotherapy.Recombinant human MIP-5/CCL15 (rhMIP-5/CCL15) produced in E.coli is a single non-glycosylated polypeptide chain containing 92 amino acids. A fully biologically active molecule, rhMIP-5/CCL15 has a molecular mass of 10.2 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.
- 序列
- QFT NDAETELMMS KLPLENPVVL NSFHFAADCC TSYISQSIPC SLMKSYFETS SECSKPGVIF LTKKGRQVCA KPSGPGVQDC MKKLKPYSI
- 來源宿主
- Escherichia coli.
- 溶解建議
- Reconstituted in ddH2O at 100 μg/mL.
- 保存建議
- Lyophilized recombinant human MIP-5/CCL15 (rhMIP-5/CCL15) remains stable up to 6 months at -80
- 其他
- Bioworld是專一服務(wù)于生命科學(xué)研究的專業(yè)技術(shù)型企業(yè),Bioworld品牌創(chuàng)立以來擁有10000多種常規(guī)產(chǎn)品現(xiàn)貨,現(xiàn)有8000多種現(xiàn)貨抗體,以及其他IVD原料,蛋白等現(xiàn)貨產(chǎn)品。在細(xì)胞信號通路、免疫學(xué)、蛋白組學(xué)上擁有顯著優(yōu)勢,其抗體產(chǎn)品、生長因子、IVD原料等為生命科學(xué)科研工作者提供了極大的便利

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