中文名稱

重組HVEM—fc，人

英文名字

RecombinantHVEM-Fc,Human

供應商

Bioworld

產(chǎn)品貨號

BK0355

產(chǎn)品報價

￥詢價/10ug

產(chǎn)品說明書

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購買方式

銀行轉賬、電匯、支票、現(xiàn)金，在線支付寶及網(wǎng)銀支付，或直接與我們電話聯(lián)系400-6800-868

產(chǎn)品新聞

背景資料

Herpes Virus Entry Mediator (HVEM) is a transmembrane protein that is the receptor for TNFSF14 (also known as LIGHT) and is therefore referred to asTNFRSF14. HVEM is expressed broadly on immune cells such as T cells, natural killer (NK) cells and monocytes. The interaction of 3 molecules of LIGHT with three molecules of HVEM forms a hexameric complex that leads to the recruitment and retention of effector cells and activates NK cells to produce large amounts of IFN-γ and GM-CSF. In addition to the canonical binding partner LIGHT, HVEM can also bind to the inhibitory signaling protein, B- and T- lymphocyte attenuator (BTLA),which suppresses immune responses. Therefore, the HVEM network plays an important role in regulating immunity and the behavior of lymphocytes.Recombinant human HVEM-Fc (rhHVEM-Fc) produced in Sf9 insect cells is a single glycosylated polypeptide chain containing 376 amino acids. A fully biologically active molecule, rhHVEM-Fc has a molecular mass of around 45 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.

序列

LPSCKED EYPVGSECCP KCSPGYRVKE ACGELTGTVC EPCPPGTYIA HLNGLSKCLQ CQMCDPAMGL RASRNCSRTE NAVCGCSPGH FCIVQDGDHC AACRAYATSS PGQRVQKGGT ESQDTLCQNC PPGTFSPNGT LEECQHQTKR SCDKTHTCPP CPAPELLGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSRDEL TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM HEALHNHYTQ KSLSLSPGK

來源宿主

SF9 insect cells

溶解建議

Reconstituted in ddH₂

保存建議

Lyophilized recombinant human HVEM-Fc (rhHVEM-Fc) remains stable up to 6 months at -80

其他

Bioworld是專一服務于生命科學研究的專業(yè)技術型企業(yè)，Bioworld品牌創(chuàng)立以來擁有10000多種常規(guī)產(chǎn)品現(xiàn)貨，現(xiàn)有8000多種現(xiàn)貨抗體，以及其他IVD原料，蛋白等現(xiàn)貨產(chǎn)品。在細胞信號通路、免疫學、蛋白組學上擁有顯著優(yōu)勢，其抗體產(chǎn)品、生長因子、IVD原料等為生命科學科研工作者提供了極大的便利

注意

該頁面的中文產(chǎn)品信息的翻譯，僅供參考。準確的產(chǎn)品信息請以廠家的英文說明書為準。下單前，請瀏覽說明書確認。

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