VASP (vasodilator-stimulated phosphoprotein), is involved in the maintenance of cytoarchitecture by interacting with actin-like filaments. VASP shares a limited degree of homology with the amino terminus of WASP, which is frequently mutated in WAS patients. An established substrate of cAMP and cGMP dependent kinases, VASP is phosphorylated on a regulatory serine residue 157 and localizes to focal adhesions, microfilaments and highly active regions of the plasma membrane.
應(yīng)用類型
WB,IHC-F,IHC-P,ICC/IF,ELISA
免疫原
The antiserum was produced against synthesized peptide derived from human VASP. AA range:124-173