Ang 1-7 is a biologically active peptide of the renin-angiotensin system. Ang I-7 binds the Mas receptor, which mediates vasodilation and the antiproliferative actions of the heptapeptide. Endogenous Ang 1-7 is generated by angiotensin-converting enzyme 2 (ACE 2) mediated degradation of Ang II. It can also be formed from Ang I or Ang II by other peptidases.
產(chǎn)品描述
Ang 1-7是腎素-血管緊張素系統(tǒng)的一種生物活性肽。 Ang I-7與Mas受體結(jié)合,后者介導(dǎo)血管舒張和七肽的抗增殖作用。 血管緊張素轉(zhuǎn)換酶2(ACE 2)介導(dǎo)的Ang II降解產(chǎn)生內(nèi)源性Ang 1-7。 它也可以由Ang I或Ang II通過(guò)其它肽酶形成。