【SAA1】重組人血清淀粉樣蛋白A-Recombinant Human Serum Amyloid A (APO-SAA1), His Tag代理/參數(shù)/廠家-蛋白標(biāo)準(zhǔn)品-艾美捷科技有限公司

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背景資料: SAA1 protein is an acute phase apolipoprotein reactant which is produced mostly by hepatocytes and under regulation of inflammatory cytokines. SAA1 （Serum amyloid A1） protein is produced mainly in the liver and circulates in low levels in the blood. The SAA1 seems to have a role in the immune system. SAA1 protein levels increase in the blood and other tissues under conditions of inflammation. SAA1 may facilitate the repair of injured tissues； it also acts as an antibacterial agent，and signals the migration of germ-fighting cells to sites of infection. SAA1 also functions as an apolipoprotein of the HDL complex.
Elevated levels of SAA1 ultimately affect secondary amyloidosis，extracellular amassing of amyloid fibrils，resulting from a circulating precursor，in a variety of tissues and organs. The most widespread type of amyloidosis appears secondary to chronic inflammatory disease，mainly rheumatoid arthritis. The SAA1 cleavage product a designated amyloid protein A is deposited systemically as amyloid in vital organs such as the liver，spleen，and kidneys in chronic inflammatory diseases patients. These deposits are extremely insoluble and resistant to proteolysis； they disrupt tissue structure and compromise performance.

溶解建議: 提供的人血清淀粉樣蛋白A（SAA1）產(chǎn)品為過濾滅菌的無色溶液；其中人血清淀粉樣蛋白A（SAA1）產(chǎn)品溶解于20mM Tris緩沖液（pH 8.0），10% 甘油溶液中.

保存建議: 人血清淀粉樣蛋白A（SAA1）溶液可以在4℃冷藏保存4周時(shí)間；如果想延長保存時(shí)間，建議分裝（加載體蛋白如0.1% HSA或 BSA）后置于-18℃凍存.請(qǐng)避免反復(fù)凍融.

其他: ProSpec 是一家全球著名細(xì)胞因子蛋白生產(chǎn)和研發(fā)的公司，具有20多年的生產(chǎn)經(jīng)驗(yàn)，專注于蛋白（重組及合成）生產(chǎn)研發(fā)。我們的核心產(chǎn)品包括：干擾素、白介素、骨蛋白、腫瘤壞死因子、成纖維生長因子、瘦素、干細(xì)胞因子、催乳素、表皮生長因子、胰島素樣生長因子、神經(jīng)生長因子、集落刺激因子、激素、酶、病毒抗原以及各種重組蛋白等。領(lǐng)先的生產(chǎn)工藝和規(guī)模使其可以提供毫克到克級(jí)蛋白，價(jià)格優(yōu)于同類公司。絕大部分產(chǎn)品是天然成熟型蛋白，而不含有標(biāo)簽蛋白。考慮到大部分研究者希望能更靈活地配制蛋白溶液，ProSpec-Tany絕大部分產(chǎn)品沒有添加保護(hù)劑或鹽，這就對(duì)工藝提出了更高的要求。同時(shí)，ProSpec-Tany絕大部分產(chǎn)品為凍干粉，因此易于運(yùn)輸和保存。