Prolactin is a lactogenic hormone secreted by the adenohypophysis .Besides its major action on lactation,in some species prolactin exerts effects on reproduction,maternal behavior,fat metabolism,immunomodulation and osmoregulation.Prolactin has been shown also to have cytokine-like activities and to have important immunoregulatory activities. It contributes to the development of lymphoid tissues and the maintenance of physiological immune function and also modulates a variety of T-cell immune responses. Prolactin has been reported to activate cellular proliferation in nonreproductive tissue,such as liver,spleen,and thymus. It induces significant proliferation in aortic smooth muscle cells and also enhances proliferation of these cells induced by PDGF . Prolactin also appears to be directly mitogenic for pancreatic beta cells. Prolactin is also mitogenic for cultured astrocytes.
序列
請咨詢我們客服或者請查看品牌官方網(wǎng)站
來源宿主
大腸桿菌中重組表達
溶解建議
提供的綿羊催乳素受體拮抗劑突變體(oPrl A Mutant)產(chǎn)品為過濾滅菌的白色凍干粉末;該凍干粉末是從含1mg/ml綿羊催乳素受體拮抗劑突變體(oPrl A Mutant)的0.02%-0.03% NaHCO3溶液中凍干產(chǎn)生的.我們建議加無菌的18MΩ-cm水以配制工作儲存液到不低于100ug/ml,后繼實驗過程中可根據(jù)實驗要求進一步稀釋.
保存建議
綿羊催乳素受體拮抗劑突變體(oPrl A Mutant)在室溫可保存3周,或置于-18℃凍存用于長期保存.重新溶解后可以在4℃冷藏保存至少2-7天;如果想延長保存時間,建議分裝(加載體蛋白如0.1% HSA或 BSA)后置于-18℃凍存.請避免反復(fù)凍融.