BioSim?Trastuzumab（Herceptin?）（人類）ELISA試劑盒-BioSim? Trastuzumab (Herceptin?)(Human) ELISA Kit代理/參數(shù)/廠家-細胞分析試劑盒-艾美捷科技有限公司

PRODUCT CENTER

細胞分析試劑盒

產品中心

當前位置：首頁 > 產品中心 > 細胞生物學產品 > 細胞分析試劑盒

產品描述: Trastuzumab (Herclon?, Herceptin?) is a recombinant DNA-derived humanized monoclonal antibody that selectively targets the extracellular domain of the human epidermal growth factor receptor 2 protein (HER2). Trastuzumab has antitumor activity against HER2-positive human breast tumor cells in laboratory models and is active for the trea?ent of women with HER2-overexpressing breast cancers. This antibody was approved in 1998 for clinical use for HER2 overexpressing metastatic breast cancer. In HER2 overexpressing cells, trastuzumab markedly down-regulates HER2 expression by accelerating receptor endocytosis and degradation and inhibits cell cycle progression by inducing the formation of p27Kip1/Cdk2 complexes. BioSim? Trastuzumab ELISA kit has been developed for specific quantification of Trastuzumab concentration in human serum or plasma with high sensitivity and reproducibility.

產品特點: ? Easy, convenient, sensitive and time-saving method to measure the level of Trastuzumab in human serum and plasma. ? Detection Range: 11 - 300 ng/ml ? Sensitivity: Quantitative limit: 11 ng/ml, Detection limit: 2 ng/ml ? Assay Precision: Intra-Assay: CV < 15%; Inter-Assay: CV < 15% (CV (%) = SD/mean X 100) ? Recovery rate: 85 – 115% with normal human serum samples with known concentrations ? Cross Reactivity: No significant cross-reactivity or interference with other proteins present in native human serum or other therapeutic immunoglobulins.

其他: BioVision的公司總部在美麗的舊金山灣地區(qū)，它是全球生命科學公司的領導者.BioVision在開發(fā)和研究細胞凋亡檢測分析、代謝檢測方面具有卓越的影響力.包括檢測各種檢測分析試劑盒、相關特色抗體、重組蛋白及細胞因子和酶等多種產品，以及其他創(chuàng)新的研究工具.其產品覆蓋細胞凋亡研究、能量代謝、細胞/組織蛋白提取、氧化應激與損傷、代謝與肥胖癥、細胞增殖與毒性、信號轉導、干細胞研究等領域.作為多家知名品牌的中國總代理以及中國區(qū)域代理，艾美捷與BioVision一起為研究者們提供最好、最新的細胞生物學研究工具而不斷擴大產品及服務質量.