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細(xì)胞分析試劑盒
中文名稱

BioSim?抗阿達(dá)木單抗(Humira?)(人類)ELISA試劑盒

英文名字
BioSim? anti-Adalimumab (Humira?) (Human) ELISA Kit
供應(yīng)商
Biovision
產(chǎn)品貨號(hào)
E4388-100
產(chǎn)品報(bào)價(jià)
¥詢價(jià)/100assays
產(chǎn)品說(shuō)明書
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產(chǎn)品新聞
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產(chǎn)品描述
Adalimumab (Humira?) is a recombinant human IgG1 monoclonal antibody specific for Tumor Necrosis Factor-Alpha (TNF-α) and is used to treat rheumatic arthritis, intestinal disorders, dermatological diseases and cancer. Adalimumab specifically binds to TNF alpha and blocks its interaction with p55 and p75 cell surface TNF receptors and reduces the inflammation and subsequently improves the patient’s health. Drug level quantification can be important to adapt patient prescription or to switch to an alternative TNF inhibitor drug. However, some patients develop unwanted immunogenicity, which leads to production of anti-drug-antibodies (ADAs) inactivating the therapeutic effects of the treatment and, in rare cases, inducing adverse effects. BioVision’s BioSimTM anti-Adalimumab ELISA kit is designed to quantify/measure the antibody against Adalimumab with high specificity and sensitivity in biological matrices.
產(chǎn)品特點(diǎn)
Easy, convenient, sensitive and time-saving method to measure the level of antibody against Adalimumab in human serum and plasma. Detection Range: 62 - 500 ng/ml Sensitivity: 30 ng/ml Assay Precision: Intra-Assay: CV < 15%; Inter-Assay: CV < 15% (CV (%) = SD/mean X 100) Cross Reactivity: Adalimumab infusion camouflages/masks the presence of antibody to adalimumab (ATA) in serum/plasma samples. Therefore, blood sampling time is critical for detection of ATA. It is convenient to obtain blood sample just before the infusion of adalimumab or at least 2 weeks after the infusion of adalimumab. Recovery rate: 85 – 115% with normal human serum samples with known concentrations
保存建議
4
其他
BioVision的公司總部在美麗的舊金山灣地區(qū),它是全球生命科學(xué)公司的領(lǐng)導(dǎo)者.BioVision在開(kāi)發(fā)和研究細(xì)胞凋亡檢測(cè)分析、代謝檢測(cè)方面具有卓越的影響力.包括檢測(cè)各種檢測(cè)分析試劑盒、相關(guān)特色抗體、重組蛋白及細(xì)胞因子和酶等多種產(chǎn)品,以及其他創(chuàng)新的研究工具.其產(chǎn)品覆蓋細(xì)胞凋亡研究、能量代謝、細(xì)胞/組織蛋白提取、氧化應(yīng)激與損傷、代謝與肥胖癥、細(xì)胞增殖與毒性、信號(hào)轉(zhuǎn)導(dǎo)、干細(xì)胞研究等領(lǐng)域.作為多家知名品牌的中國(guó)總代理以及中國(guó)區(qū)域代理,艾美捷與BioVision一起為研究者們提供最好、最新的細(xì)胞生物學(xué)研究工具而不斷擴(kuò)大產(chǎn)品及服務(wù)質(zhì)量.
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