BioSim?抗Golimumab（Simponi?）（人類）ELISA試劑盒-BioSim? anti-Golimumab (Simponi?) (Human) ELISA Kit代理/參數(shù)/廠家-細胞分析試劑盒-艾美捷科技有限公司

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產(chǎn)品描述: Golimumab (Simponi?) is a human immunoglobulin G1κ monoclonal antibody which is specific for pro-inflammatory cytokine, tumor necrosis factor-α (TNFα). Elevated levels of TNF are found in the synovial fluid of rheumatoid arthritis, including juvenile idiopathic arthritis, psoriatic arthritis, and ankylosing spondylitis patients and play an important role in both the pathologic inflammation and the joint destruction that are hallmarks of these diseases. Golimumab binds to both the soluble and transmembrane bioactive forms of human TNF and prevent TNF from binding to its receptors and finally inhibits biological activity of TNF. However, some patients develop unwanted immunogenicity, which leads to production of anti-drug-antibodies (ADAs) inactivating the therapeutic effects of the treatment and, in rare cases, inducing adverse effects. BioVision’s BioSimTM anti-Golimumab ELISA kit is designed to detect the antibody against Golimumab with high specificity and sensitivity in biological matrices.

產(chǎn)品特點: Easy, convenient, sensitive and time-saving method toqualitative determination of antibody against Golimumab (Simponi) in human serum and plasma. Cross Reactivity: Golimumab (Simponi) infusion camouflages/masks the presence of antibody to Etanercept (ATC) in serum/plasma samples. Therefore, blood sampling time is critical for detection of ATC. It is convenient to obtain blood sample just before the infusion or at least 2 weeks after the infusion of Golimumab.

其他: BioVision的公司總部在美麗的舊金山灣地區(qū)，它是全球生命科學公司的領(lǐng)導(dǎo)者.BioVision在開發(fā)和研究細胞凋亡檢測分析、代謝檢測方面具有卓越的影響力.包括檢測各種檢測分析試劑盒、相關(guān)特色抗體、重組蛋白及細胞因子和酶等多種產(chǎn)品，以及其他創(chuàng)新的研究工具.其產(chǎn)品覆蓋細胞凋亡研究、能量代謝、細胞/組織蛋白提取、氧化應(yīng)激與損傷、代謝與肥胖癥、細胞增殖與毒性、信號轉(zhuǎn)導(dǎo)、干細胞研究等領(lǐng)域.作為多家知名品牌的中國總代理以及中國區(qū)域代理，艾美捷與BioVision一起為研究者們提供最好、最新的細胞生物學研究工具而不斷擴大產(chǎn)品及服務(wù)質(zhì)量.